Zhang Y - Search Results

1

Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice.

Chai AC, Cui M, Chemello F, Li H, Chen K, Tan W, Atmanli A, McAnally JR, Zhang Y, Xu L, Liu N, Bassel-Duby R, Olson EN. Chai AC, et al. Among authors: zhang y. Nat Med. 2023 Feb;29(2):401-411. doi: 10.1038/s41591-022-02176-5. Epub 2023 Feb 16. Nat Med. 2023. PMID: 36797478 Free PMC article.

2

Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy.

Nishiyama T, Zhang Y, Cui M, Li H, Sanchez-Ortiz E, McAnally JR, Tan W, Kim J, Chen K, Xu L, Bassel-Duby R, Olson EN. Nishiyama T, et al. Among authors: zhang y. Sci Transl Med. 2022 Nov 23;14(672):eade1633. doi: 10.1126/scitranslmed.ade1633. Epub 2022 Nov 23. Sci Transl Med. 2022. PMID: 36417486 Free PMC article.

3

CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice.

Zhang Y, Long C, Li H, McAnally JR, Baskin KK, Shelton JM, Bassel-Duby R, Olson EN. Zhang Y, et al. Sci Adv. 2017 Apr 12;3(4):e1602814. doi: 10.1126/sciadv.1602814. eCollection 2017 Apr. Sci Adv. 2017. PMID: 28439558 Free PMC article.

4

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing.

Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, Zhang Y, Min YL, Shelton JM, Mammen PPA, Liaw NY, Zimmermann WH, Bassel-Duby R, Schneider JW, Olson EN. Long C, et al. Among authors: zhang y. Sci Adv. 2018 Jan 31;4(1):eaap9004. doi: 10.1126/sciadv.aap9004. eCollection 2018 Jan. Sci Adv. 2018. PMID: 29404407 Free PMC article.

5

Myoediting: Toward Prevention of Muscular Dystrophy by Therapeutic Genome Editing.

Zhang Y, Long C, Bassel-Duby R, Olson EN. Zhang Y, et al. Physiol Rev. 2018 Jul 1;98(3):1205-1240. doi: 10.1152/physrev.00046.2017. Physiol Rev. 2018. PMID: 29717930 Free PMC article. Review.

6

In vivo non-invasive monitoring of dystrophin correction in a new Duchenne muscular dystrophy reporter mouse.

Amoasii L, Li H, Zhang Y, Min YL, Sanchez-Ortiz E, Shelton JM, Long C, Mireault AA, Bhattacharyya S, McAnally JR, Bassel-Duby R, Olson EN. Amoasii L, et al. Among authors: zhang y. Nat Commun. 2019 Oct 4;10(1):4537. doi: 10.1038/s41467-019-12335-x. Nat Commun. 2019. PMID: 31586095 Free PMC article.

7

Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system.

Zhang Y, Li H, Min YL, Sanchez-Ortiz E, Huang J, Mireault AA, Shelton JM, Kim J, Mammen PPA, Bassel-Duby R, Olson EN. Zhang Y, et al. Sci Adv. 2020 Feb 19;6(8):eaay6812. doi: 10.1126/sciadv.aay6812. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128412 Free PMC article.

8

Correction of Three Prominent Mutations in Mouse and Human Models of Duchenne Muscular Dystrophy by Single-Cut Genome Editing.

Min YL, Chemello F, Li H, Rodriguez-Caycedo C, Sanchez-Ortiz E, Mireault AA, McAnally JR, Shelton JM, Zhang Y, Bassel-Duby R, Olson EN. Min YL, et al. Among authors: zhang y. Mol Ther. 2020 Sep 2;28(9):2044-2055. doi: 10.1016/j.ymthe.2020.05.024. Epub 2020 May 30. Mol Ther. 2020. PMID: 32892813 Free PMC article.

9

A consolidated AAV system for single-cut CRISPR correction of a common Duchenne muscular dystrophy mutation.

Zhang Y, Nishiyama T, Li H, Huang J, Atmanli A, Sanchez-Ortiz E, Wang Z, Mireault AA, Mammen PPA, Bassel-Duby R, Olson EN. Zhang Y, et al. Mol Ther Methods Clin Dev. 2021 Jun 4;22:122-132. doi: 10.1016/j.omtm.2021.05.014. eCollection 2021 Sep 10. Mol Ther Methods Clin Dev. 2021. PMID: 34485599 Free PMC article.

10

CRISPR/Cas correction of muscular dystrophies.

Zhang Y, Nishiyama T, Olson EN, Bassel-Duby R. Zhang Y, et al. Exp Cell Res. 2021 Nov 1;408(1):112844. doi: 10.1016/j.yexcr.2021.112844. Epub 2021 Sep 25. Exp Cell Res. 2021. PMID: 34571006 Free PMC article.

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