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Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis.
Zhang Y, Cedervall J, Hamidi A, Herre M, Viitaniemi K, D'Amico G, Miao Z, Unnithan RVM, Vaccaro A, van Hooren L, Georganaki M, Thulin Å, Qiao Q, Andrae J, Siegbahn A, Heldin CH, Alitalo K, Betsholtz C, Dimberg A, Olsson AK. Zhang Y, et al. Cancer Res. 2020 Aug 15;80(16):3345-3358. doi: 10.1158/0008-5472.CAN-19-3533. Epub 2020 Jun 25. Cancer Res. 2020. PMID: 32586981
TANK-binding kinase 1 is a mediator of platelet-induced EMT in mammary carcinoma cells.
Zhang Y, Unnithan RVM, Hamidi A, Caja L, Saupe F, Moustakas A, Cedervall J, Olsson AK. Zhang Y, et al. FASEB J. 2019 Jul;33(7):7822-7832. doi: 10.1096/fj.201801936RRR. Epub 2019 Mar 26. FASEB J. 2019. PMID: 30912981
Altogether, these results suggest that TBK1 contributes to tumor invasiveness and may be a driver of metastatic spread in breast cancer.-Zhang, Y., Unnithan, R. V. M., Hamidi, A., Caja, L., Saupe, F., Moustakas, A., Cedervall, J., Olsson, A....
Altogether, these results suggest that TBK1 contributes to tumor invasiveness and may be a driver of metastatic spread in breast cancer.- …
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