Zhang Y - Search Results

1

Machine learning-aided engineering of hydrolases for PET depolymerization.

Lu H, Diaz DJ, Czarnecki NJ, Zhu C, Kim W, Shroff R, Acosta DJ, Alexander BR, Cole HO, Zhang Y, Lynd NA, Ellington AD, Alper HS. Lu H, et al. Among authors: zhang y. Nature. 2022 Apr;604(7907):662-667. doi: 10.1038/s41586-022-04599-z. Epub 2022 Apr 27. Nature. 2022. PMID: 35478237

2

Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.

Mayfield JE, Fan S, Wei S, Zhang M, Li B, Ellington AD, Etzkorn FA, Zhang YJ. Mayfield JE, et al. ACS Chem Biol. 2015 Oct 16;10(10):2405-14. doi: 10.1021/acschembio.5b00296. Epub 2015 Sep 15. ACS Chem Biol. 2015. PMID: 26332362 Free PMC article.

3

Using fungible biosensors to evolve improved alkaloid biosyntheses.

d'Oelsnitz S, Kim W, Burkholder NT, Javanmardi K, Thyer R, Zhang Y, Alper HS, Ellington AD. d'Oelsnitz S, et al. Among authors: zhang y. Nat Chem Biol. 2022 Sep;18(9):981-989. doi: 10.1038/s41589-022-01072-w. Epub 2022 Jul 7. Nat Chem Biol. 2022. PMID: 35799063

4

Elucidation of divergent desaturation pathways in the formation of vinyl isonitrile and isocyanoacrylate.

Kim W, Chen TY, Cha L, Zhou G, Xing K, Canty NK, Zhang Y, Chang WC. Kim W, et al. Among authors: zhang y. Nat Commun. 2022 Sep 12;13(1):5343. doi: 10.1038/s41467-022-32870-4. Nat Commun. 2022. PMID: 36097268 Free PMC article.

5

Structural Basis for the Effects of Phenylalanine on Tuning the Reduction Potential of Type 1 Copper in Azurin.

Liu Y, Marshall NM, Yu SS, Kim W, Gao YG, Robinson H, Nilges MJ, Zhang Y, New SY, Lu Y. Liu Y, et al. Among authors: zhang y. Inorg Chem. 2023 Jul 24;62(29):11618-11625. doi: 10.1021/acs.inorgchem.3c01365. Epub 2023 Jul 9. Inorg Chem. 2023. PMID: 37424080

6

Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme.

d'Oelsnitz S, Diaz DJ, Kim W, Acosta DJ, Dangerfield TL, Schechter MW, Minus MB, Howard JR, Do H, Loy JM, Alper HS, Zhang YJ, Ellington AD. d'Oelsnitz S, et al. Among authors: zhang yj. Nat Commun. 2024 Mar 7;15(1):2084. doi: 10.1038/s41467-024-46356-y. Nat Commun. 2024. PMID: 38453941 Free PMC article.

7

Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme.

Yan W, Song H, Song F, Guo Y, Wu CH, Her AS, Pu Y, Wang S, Naowarojna N, Weitz A, Hendrich MP, Costello CE, Zhang L, Liu P, Zhang YJ. Yan W, et al. Among authors: zhang l, zhang yj. Nature. 2015 Nov 26;527(7579):539-543. doi: 10.1038/nature15519. Epub 2015 Nov 2. Nature. 2015. PMID: 26524521 Free PMC article. Retracted.

8

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth.

Cramer SL, Saha A, Liu J, Tadi S, Tiziani S, Yan W, Triplett K, Lamb C, Alters SE, Rowlinson S, Zhang YJ, Keating MJ, Huang P, DiGiovanni J, Georgiou G, Stone E. Cramer SL, et al. Nat Med. 2017 Jan;23(1):120-127. doi: 10.1038/nm.4232. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869804 Free PMC article.

9

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain.

Portz B, Lu F, Gibbs EB, Mayfield JE, Rachel Mehaffey M, Zhang YJ, Brodbelt JS, Showalter SA, Gilmour DS. Portz B, et al. Nat Commun. 2017 May 12;8:15231. doi: 10.1038/ncomms15231. Nat Commun. 2017. PMID: 28497792 Free PMC article.

10

Phosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain.

Gibbs EB, Lu F, Portz B, Fisher MJ, Medellin BP, Laremore TN, Zhang YJ, Gilmour DS, Showalter SA. Gibbs EB, et al. Nat Commun. 2017 May 12;8:15233. doi: 10.1038/ncomms15233. Nat Commun. 2017. PMID: 28497798 Free PMC article.

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