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Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.
Chapman OS, Luebeck J, Sridhar S, Wong IT, Dixit D, Wang S, Prasad G, Rajkumar U, Pagadala MS, Larson JD, He BJ, Hung KL, Lange JT, Dehkordi SR, Chandran S, Adam M, Morgan L, Wani S, Tiwari A, Guccione C, Lin Y, Dutta A, Lo YY, Juarez E, Robinson JT, Korshunov A, Michaels JA, Cho YJ, Malicki DM, Coufal NG, Levy ML, Hobbs C, Scheuermann RH, Crawford JR, Pomeroy SL, Rich JN, Zhang X, Chang HY, Dixon JR, Bagchi A, Deshpande AJ, Carter H, Fraenkel E, Mischel PS, Wechsler-Reya RJ, Bafna V, Mesirov JP, Chavez L. Chapman OS, et al. Among authors: zhang x. Nat Genet. 2023 Dec;55(12):2189-2199. doi: 10.1038/s41588-023-01551-3. Epub 2023 Nov 9. Nat Genet. 2023. PMID: 37945900 Free PMC article.
Strength of immune selection in tumors varies with sex and age.
Castro A, Pyke RM, Zhang X, Thompson WK, Day CP, Alexandrov LB, Zanetti M, Carter H. Castro A, et al. Among authors: zhang x. Nat Commun. 2020 Aug 17;11(1):4128. doi: 10.1038/s41467-020-17981-0. Nat Commun. 2020. PMID: 32807809 Free PMC article.
MHC-I genotype and tumor mutational burden predict response to immunotherapy.
Goodman AM, Castro A, Pyke RM, Okamura R, Kato S, Riviere P, Frampton G, Sokol E, Zhang X, Ball ED, Carter H, Kurzrock R. Goodman AM, et al. Among authors: zhang x. Genome Med. 2020 May 19;12(1):45. doi: 10.1186/s13073-020-00743-4. Genome Med. 2020. PMID: 32430031 Free PMC article.
Lead Time to Recurrence After Posttreatment Plasma and Saliva HPV DNA Testing in Patients With Low-Risk HPV Oropharynx Cancer.
Califano J, Yousef A, Mostafa H, Valsamakis A, Zhang X, Batis N, Varghese C, Parish J, Forman M, Jarrett J, Messer K, Mehanna H. Califano J, et al. Among authors: zhang x. JAMA Otolaryngol Head Neck Surg. 2023 Sep 1;149(9):812-819. doi: 10.1001/jamaoto.2023.1730. JAMA Otolaryngol Head Neck Surg. 2023. PMID: 37498566 Clinical Trial.
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