Kartogenin preconditioning commits mesenchymal stem cells to a precartilaginous stage with enhanced chondrogenic potential by modulating JNK and β-catenin-related pathways.
Jing H, Zhang X, Gao M, Luo K, Fu W, Yin M, Wang W, Zhu Z, Zheng J, He X.
Jing H, et al. Among authors: zhang x.
FASEB J. 2019 Apr;33(4):5641-5653. doi: 10.1096/fj.201802137RRR. Epub 2019 Jan 29.
FASEB J. 2019.
PMID: 30694703
Furthermore, the KGN-preconditioned hUCMSCs efficiently differentiated into chondrocytes with elevated chondrogenic gene ( SOX9, aggrecan, and collagen II) expression and reduced expression of ossific genes (collagen X and MMP13) compared with hUCMSCs treated with TGF-beta …
Furthermore, the KGN-preconditioned hUCMSCs efficiently differentiated into chondrocytes with elevated chondrogenic gene ( SOX9, aggrecan, a …