Zhang X - Search Results

1

Design, synthesis and activity evaluation of novel lesinurad analogues containing thienopyrimidinone or pyridine substructure as human urate transporter 1 inhibitors.

Zhang J, Dong Y, Gao S, Zhang X, Liao H, Shi X, Zhang Z, Zhao T, Liang R, Qi D, Wu T, Pang J, Liu X, Zhan P. Zhang J, et al. Among authors: zhang z, zhang x. Eur J Med Chem. 2022 Dec 15;244:114816. doi: 10.1016/j.ejmech.2022.114816. Epub 2022 Oct 4. Eur J Med Chem. 2022. PMID: 36219903

2

5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase.

Sun L, Gao P, Dong G, Zhang X, Cheng X, Ding X, Wang X, Daelemans D, De Clercq E, Pannecouque C, Menéndez-Arias L, Zhan P, Liu X. Sun L, et al. Among authors: zhang x. Eur J Med Chem. 2018 Jul 15;155:714-724. doi: 10.1016/j.ejmech.2018.06.036. Epub 2018 Jun 18. Eur J Med Chem. 2018. PMID: 29940462

3

An insight on medicinal aspects of novel HIV-1 capsid protein inhibitors.

Sun L, Zhang X, Xu S, Huang T, Song S, Cherukupalli S, Zhan P, Liu X. Sun L, et al. Among authors: zhang x. Eur J Med Chem. 2021 May 5;217:113380. doi: 10.1016/j.ejmech.2021.113380. Epub 2021 Mar 15. Eur J Med Chem. 2021. PMID: 33751981 Review.

4

Discovery of potent and selective Cdc25 phosphatase inhibitors via rapid assembly and in situ screening of Quinonoid-focused libraries.

Tao Y, Hao X, Jing L, Sun L, Cherukupalli S, Liu S, Wu G, Xu S, Zhang X, Shi X, Song Y, Liu X, Zhan P. Tao Y, et al. Among authors: zhang x. Bioorg Chem. 2021 Oct;115:105254. doi: 10.1016/j.bioorg.2021.105254. Epub 2021 Aug 9. Bioorg Chem. 2021. PMID: 34426152

5

Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors.

Zhang X, Sun L, Meuser ME, Zalloum WA, Xu S, Huang T, Cherukupalli S, Jiang X, Ding X, Tao Y, Kang D, De Clercq E, Pannecouque C, Dick A, Cocklin S, Liu X, Zhan P. Zhang X, et al. Eur J Med Chem. 2021 Dec 15;226:113848. doi: 10.1016/j.ejmech.2021.113848. Epub 2021 Sep 16. Eur J Med Chem. 2021. PMID: 34592608 Free PMC article.

6

Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability.

Xu S, Sun L, Dick A, Zalloum WA, Huang T, Meuser ME, Zhang X, Tao Y, Cherukupalli S, Ding D, Ding X, Gao S, Jiang X, Kang D, De Clercq E, Pannecouque C, Cocklin S, Liu X, Zhan P. Xu S, et al. Among authors: zhang x. Eur J Med Chem. 2022 Jan 5;227:113903. doi: 10.1016/j.ejmech.2021.113903. Epub 2021 Oct 9. Eur J Med Chem. 2022. PMID: 34653770 Free PMC article.

7

Indolylarylsulfones bearing phenylboronic acid and phenylboronate ester functionalities as potent HIV‑1 non-nucleoside reverse transcriptase inhibitors.

Xu S, Song S, Sun L, Gao P, Gao S, Ma Y, Kang D, Cheng Y, Zhang X, Cherukupalli S, De Clercq E, Pannecouque C, Liu X, Zhan P. Xu S, et al. Among authors: zhang x. Bioorg Med Chem. 2022 Jan 1;53:116531. doi: 10.1016/j.bmc.2021.116531. Epub 2021 Dec 3. Bioorg Med Chem. 2022. PMID: 34890994

8

Newly Emerging Strategies in Antiviral Drug Discovery: Dedicated to Prof. Dr. Erik De Clercq on Occasion of His 80th Anniversary.

Xu S, Ding D, Zhang X, Sun L, Kang D, Huang B, Liu X, Zhan P. Xu S, et al. Among authors: zhang x. Molecules. 2022 Jan 27;27(3):850. doi: 10.3390/molecules27030850. Molecules. 2022. PMID: 35164129 Free PMC article. Review.

9

HIV-1 capsid inhibitors: a sword to destroy the virus.

Zhang X, Xu S, Sun L, Ding D, Tao Y, Kang D, Liu X, Zhan P. Zhang X, et al. Future Med Chem. 2022 May;14(9):605-607. doi: 10.4155/fmc-2022-0008. Epub 2022 Mar 17. Future Med Chem. 2022. PMID: 35297282 No abstract available.

10

Discovery of novel 1,2,4-triazole phenylalanine derivatives targeting an unexplored region within the interprotomer pocket of the HIV capsid protein.

Jiang X, Sharma PP, Rathi B, Ji X, Hu L, Gao Z, Kang D, Wang Z, Xie M, Xu S, Zhang X, De Clercq E, Cocklin S, Pannecouque C, Dick A, Liu X, Zhan P. Jiang X, et al. Among authors: zhang x. J Med Virol. 2022 Dec;94(12):5975-5986. doi: 10.1002/jmv.28064. Epub 2022 Aug 18. J Med Virol. 2022. PMID: 35949003 Free PMC article.

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