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Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts.
Li D, Wang C, Li Z, Wang H, He J, Zhu J, Zhang Y, Shen C, Xiao F, Gao Y, Zhang X, Li Y, Wang P, Peng J, Cai G, Zuo B, Yang Y, Shen Y, Song W, Zhang X, Shen L, Chen X. Li D, et al. Among authors: zhang x, zhang y. Cell Death Dis. 2018 Aug 6;9(8):840. doi: 10.1038/s41419-018-0862-9. Cell Death Dis. 2018. PMID: 30082761 Free PMC article.
The inhibition of RANKL expression in fibroblasts attenuate CoCr particles induced aseptic prosthesis loosening via the MyD88-independent TLR signaling pathway.
Li D, Wang H, Li Z, Wang C, Xiao F, Gao Y, Zhang X, Wang P, Peng J, Cai G, Zuo B, Shen Y, Qi J, Qian N, Deng L, Song W, Zhang X, Shen L, Chen X. Li D, et al. Among authors: zhang x. Biochem Biophys Res Commun. 2018 Sep 5;503(2):1115-1122. doi: 10.1016/j.bbrc.2018.06.128. Epub 2018 Jun 25. Biochem Biophys Res Commun. 2018. PMID: 29940143
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