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IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor.
Liu Y, Zhou N, Zhou L, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B. Liu Y, et al. Among authors: zhang c, zhang t, zhang h. Nat Immunol. 2021 Mar;22(3):358-369. doi: 10.1038/s41590-020-00850-9. Epub 2021 Jan 11. Nat Immunol. 2021. PMID: 33432230
Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles.
Ma J, Zhang Y, Tang K, Zhang H, Yin X, Li Y, Xu P, Sun Y, Ma R, Ji T, Chen J, Zhang S, Zhang T, Luo S, Jin Y, Luo X, Li C, Gong H, Long Z, Lu J, Hu Z, Cao X, Wang N, Yang X, Huang B. Ma J, et al. Among authors: zhang s, zhang t, zhang h, zhang y. Cell Res. 2016 Jun;26(6):713-27. doi: 10.1038/cr.2016.53. Epub 2016 May 10. Cell Res. 2016. PMID: 27167569 Free PMC article. Clinical Trial.
Chemotherapeutic tumor microparticles combining low-dose irradiation reprogram tumor-promoting macrophages through a tumor-repopulating cell-curtailing pathway.
Sun Y, Zheng Z, Zhang H, Yu Y, Ma J, Tang K, Xu P, Ji T, Liang X, Chen D, Jin X, Zhang T, Long Z, Liu Y, Huang B. Sun Y, et al. Among authors: zhang t, zhang h. Oncoimmunology. 2017 Mar 31;6(6):e1309487. doi: 10.1080/2162402X.2017.1309487. eCollection 2017. Oncoimmunology. 2017. PMID: 28680743 Free PMC article.
STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells.
Liu Y, Lv J, Liu J, Liang X, Jin X, Xie J, Zhang L, Chen D, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Jia Q, Zhu B, Kong Y, Guo J, Zhang H, Hu ZW, Cao X, Qin FX, Huang B. Liu Y, et al. Among authors: zhang l, zhang t, zhang h. J Clin Invest. 2018 Mar 1;128(3):1057-1073. doi: 10.1172/JCI96329. Epub 2018 Feb 12. J Clin Invest. 2018. PMID: 29431732 Free PMC article.
Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation.
Liu Y, Liang X, Dong W, Fang Y, Lv J, Zhang T, Fiskesund R, Xie J, Liu J, Yin X, Jin X, Chen D, Tang K, Ma J, Zhang H, Yu J, Yan J, Liang H, Mo S, Cheng F, Zhou Y, Zhang H, Wang J, Li J, Chen Y, Cui B, Hu ZW, Cao X, Xiao-Feng Qin F, Huang B. Liu Y, et al. Among authors: zhang t, zhang h. Cancer Cell. 2018 Mar 12;33(3):480-494.e7. doi: 10.1016/j.ccell.2018.02.005. Cancer Cell. 2018. PMID: 29533786 Free article.
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