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Increasing cell size remodels the proteome and promotes senescence.
Lanz MC, Zatulovskiy E, Swaffer MP, Zhang L, Ilerten I, Zhang S, You DS, Marinov G, McAlpine P, Elias JE, Skotheim JM. Lanz MC, et al. Among authors: zhang l, zhang s. Mol Cell. 2022 Sep 1;82(17):3255-3269.e8. doi: 10.1016/j.molcel.2022.07.017. Epub 2022 Aug 19. Mol Cell. 2022. PMID: 35987199 Free PMC article.
RB depletion is required for the continuous growth of tumors initiated by loss of RB.
Doan A, Arand J, Gong D, Drainas AP, Shue YT, Lee MC, Zhang S, Walter DM, Chaikovsky AC, Feldser DM, Vogel H, Dow LE, Skotheim JM, Sage J. Doan A, et al. Among authors: zhang s. PLoS Genet. 2021 Dec 8;17(12):e1009941. doi: 10.1371/journal.pgen.1009941. eCollection 2021 Dec. PLoS Genet. 2021. PMID: 34879057 Free PMC article.
Delineation of proteome changes driven by cell size and growth rate.
Zatulovskiy E, Lanz MC, Zhang S, McCarthy F, Elias JE, Skotheim JM. Zatulovskiy E, et al. Among authors: zhang s. Front Cell Dev Biol. 2022 Sep 5;10:980721. doi: 10.3389/fcell.2022.980721. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36133920 Free PMC article.
Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration.
Sun X, Chuang JC, Kanchwala M, Wu L, Celen C, Li L, Liang H, Zhang S, Maples T, Nguyen LH, Wang SC, Signer RA, Sorouri M, Nassour I, Liu X, Xu J, Wu M, Zhao Y, Kuo YC, Wang Z, Xing C, Zhu H. Sun X, et al. Among authors: zhang s. Cell Stem Cell. 2016 Apr 7;18(4):456-66. doi: 10.1016/j.stem.2016.03.001. Epub 2016 Mar 24. Cell Stem Cell. 2016. PMID: 27044474 Free PMC article.
Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
Lin YH, Zhang S, Zhu M, Lu T, Chen K, Wen Z, Wang S, Xiao G, Luo D, Jia Y, Li L, MacConmara M, Hoshida Y, Singal AG, Yopp A, Wang T, Zhu H. Lin YH, et al. Among authors: zhang s. Gastroenterology. 2020 May;158(6):1698-1712.e14. doi: 10.1053/j.gastro.2020.01.026. Epub 2020 Jan 20. Gastroenterology. 2020. PMID: 31972235 Free PMC article.
The Polyploid State Plays a Tumor-Suppressive Role in the Liver.
Zhang S, Zhou K, Luo X, Li L, Tu HC, Sehgal A, Nguyen LH, Zhang Y, Gopal P, Tarlow BD, Siegwart DJ, Zhu H. Zhang S, et al. Among authors: zhang y. Dev Cell. 2018 Feb 26;44(4):447-459.e5. doi: 10.1016/j.devcel.2018.01.010. Epub 2018 Feb 8. Dev Cell. 2018. PMID: 29429824 Free PMC article.
77,781 results
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