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Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring.
Nicholas LM, Rattanatray L, MacLaughlin SM, Ozanne SE, Kleemann DO, Walker SK, Morrison JL, Zhang S, Muhlhäusler BS, Martin-Gronert MS, McMillen IC. Nicholas LM, et al. Among authors: zhang s. FASEB J. 2013 Sep;27(9):3786-96. doi: 10.1096/fj.13-227918. Epub 2013 May 31. FASEB J. 2013. PMID: 23729590
Impact of embryo number and periconceptional undernutrition on factors regulating adipogenesis, lipogenesis, and metabolism in adipose tissue in the sheep fetus.
Lie S, Morrison JL, Williams-Wyss O, Ozanne SE, Zhang S, Walker SK, Kleemann DO, MacLaughlin SM, Roberts CT, McMillen IC. Lie S, et al. Among authors: zhang s. Am J Physiol Endocrinol Metab. 2013 Oct 15;305(8):E931-41. doi: 10.1152/ajpendo.00180.2013. Epub 2013 Aug 6. Am J Physiol Endocrinol Metab. 2013. PMID: 23921136 Free article.
Dietary restriction in the periconceptional period in normal-weight or obese ewes results in increased abundance of angiotensin-converting enzyme (ACE) and angiotensin type 1 receptor (AT1R) in the absence of changes in ACE or AT1R methylation in the adrenal of the offspring.
Zhang S, Morrison JL, Gill A, Rattanatray L, MacLaughlin SM, Kleemann D, Walker SK, McMillen IC. Zhang S, et al. Reproduction. 2013 Oct 1;146(5):443-54. doi: 10.1530/REP-13-0219. Print 2013. Reproduction. 2013. PMID: 24084173
Maternal dietary restriction during the periconceptional period in normal-weight or obese ewes results in adrenocortical hypertrophy, an up-regulation of the JAK/STAT and down-regulation of the IGF1R signaling pathways in the adrenal of the postnatal lamb.
Zhang S, Morrison JL, Gill A, Rattanatray L, MacLaughlin SM, Kleemann D, Walker SK, McMillen IC. Zhang S, et al. Endocrinology. 2013 Dec;154(12):4650-62. doi: 10.1210/en.2013-1414. Epub 2013 Oct 9. Endocrinology. 2013. PMID: 24108072 Free PMC article. Clinical Trial.
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