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Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro.
Hou N, Shuai L, Zhang L, Xie X, Tang K, Zhu Y, Yu Y, Zhang W, Tan Q, Zhong G, Wen Z, Wang C, He X, Huo H, Gao H, Xu Y, Xue J, Peng C, Zou J, Schindewolf C, Menachery V, Su W, Yuan Y, Shen Z, Zhang R, Yuan S, Yu H, Shi PY, Bu Z, Huang J, Hu Q. Hou N, et al. Among authors: zhang l, zhang r, zhang w. ACS Cent Sci. 2023 Jan 25;9(2):217-227. doi: 10.1021/acscentsci.2c01359. eCollection 2023 Feb 22. ACS Cent Sci. 2023. PMID: 36844503 Free PMC article.
A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.
Zhu Y, Feng F, Hu G, Wang Y, Yu Y, Zhu Y, Xu W, Cai X, Sun Z, Han W, Ye R, Qu D, Ding Q, Huang X, Chen H, Xu W, Xie Y, Cai Q, Yuan Z, Zhang R. Zhu Y, et al. Among authors: zhang r. Nat Commun. 2021 Feb 11;12(1):961. doi: 10.1038/s41467-021-21213-4. Nat Commun. 2021. PMID: 33574281 Free PMC article.
Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2.
Liu Y, Hu G, Wang Y, Ren W, Zhao X, Ji F, Zhu Y, Feng F, Gong M, Ju X, Zhu Y, Cai X, Lan J, Guo J, Xie M, Dong L, Zhu Z, Na J, Wu J, Lan X, Xie Y, Wang X, Yuan Z, Zhang R, Ding Q. Liu Y, et al. Among authors: zhang r. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2025373118. doi: 10.1073/pnas.2025373118. Proc Natl Acad Sci U S A. 2021. PMID: 33658332 Free PMC article.
A novel cell culture system modeling the SARS-CoV-2 life cycle.
Ju X, Zhu Y, Wang Y, Li J, Zhang J, Gong M, Ren W, Li S, Zhong J, Zhang L, Zhang QC, Zhang R, Ding Q. Ju X, et al. Among authors: zhang l, zhang r, zhang j, zhang qc. PLoS Pathog. 2021 Mar 12;17(3):e1009439. doi: 10.1371/journal.ppat.1009439. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33711082 Free PMC article.
Protein Kinase C Inhibitors Reduce SARS-CoV-2 Replication in Cultured Cells.
Huang C, Feng F, Shi Y, Li W, Wang Z, Zhu Y, Yuan S, Hu D, Dai J, Jiang Q, Zhang R, Liu C, Zhang P. Huang C, et al. Among authors: zhang r, zhang p. Microbiol Spectr. 2022 Oct 26;10(5):e0105622. doi: 10.1128/spectrum.01056-22. Epub 2022 Aug 24. Microbiol Spectr. 2022. PMID: 36000889 Free PMC article.
A CRISPR activation screen identifies genes that enhance SARS-CoV-2 infection.
Feng F, Zhu Y, Ma Y, Wang Y, Yu Y, Sun X, Song Y, Shao Z, Huang X, Liao Y, Ma J, He Y, Wang M, Tang L, Huang Y, Zhao J, Ding Q, Xie Y, Cai Q, Xiao H, Li C, Yuan Z, Zhang R. Feng F, et al. Among authors: zhang r. Protein Cell. 2022 Aug 23;14(1):64-68. doi: 10.1093/procel/pwac036. eCollection 2023 Jan. Protein Cell. 2022. PMID: 36726758 Free PMC article. No abstract available.
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