Zhang L - Search Results

1

Recent advances of quinones as a privileged structure in drug discovery.

Zhang L, Zhang G, Xu S, Song Y. Zhang L, et al. Among authors: zhang g. Eur J Med Chem. 2021 Nov 5;223:113632. doi: 10.1016/j.ejmech.2021.113632. Epub 2021 Jun 15. Eur J Med Chem. 2021. PMID: 34153576 Review.

2

Discovery, optimization and biological evaluation for novel c-Met kinase inhibitors.

Yuan H, Liu Q, Zhang L, Hu S, Chen T, Li H, Chen Y, Xu Y, Lu T. Yuan H, et al. Among authors: zhang l. Eur J Med Chem. 2018 Jan 1;143:491-502. doi: 10.1016/j.ejmech.2017.11.073. Epub 2017 Dec 2. Eur J Med Chem. 2018. PMID: 29202410

3

Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo.

Wang LL, Kong L, Liu H, Zhang Y, Zhang L, Liu X, Yuan F, Li Y, Zuo Z. Wang LL, et al. Among authors: zhang l, zhang y. Eur J Med Chem. 2019 Nov 15;182:111665. doi: 10.1016/j.ejmech.2019.111665. Epub 2019 Aug 30. Eur J Med Chem. 2019. PMID: 31494469

4

Discovery of 4-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia.

Wang Y, Zhi Y, Jin Q, Lu S, Lin G, Yuan H, Yang T, Wang Z, Yao C, Ling J, Guo H, Li T, Jin J, Li B, Zhang L, Chen Y, Lu T. Wang Y, et al. Among authors: zhang l. J Med Chem. 2018 Feb 22;61(4):1499-1518. doi: 10.1021/acs.jmedchem.7b01261. Epub 2018 Feb 12. J Med Chem. 2018. PMID: 29357250

5

Discovery of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as novel, potent and selective c-Met kinase inhibitors: Synthesis, SAR study, and biological activity.

Zhang L, Zhao J, Zhang B, Lu T, Chen Y. Zhang L, et al. Among authors: zhang b. Eur J Med Chem. 2018 Apr 25;150:809-816. doi: 10.1016/j.ejmech.2018.03.049. Epub 2018 Mar 21. Eur J Med Chem. 2018. PMID: 29602036

6

Anti-tumor activity evaluation of novel tubulin and HDAC dual-targeting inhibitors.

Wang B, Chen X, Gao J, Su L, Zhang L, Xu H, Luan Y. Wang B, et al. Among authors: zhang l. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2638-2645. doi: 10.1016/j.bmcl.2019.07.045. Epub 2019 Jul 24. Bioorg Med Chem Lett. 2019. PMID: 31400938

7

Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents.

Jiang J, Sun B, Wang YY, Cui M, Zhang L, Cui CZ, Wang YF, Liu XG, Lou HX. Jiang J, et al. Among authors: zhang l. Bioorg Med Chem. 2012 Apr 1;20(7):2382-91. doi: 10.1016/j.bmc.2012.02.004. Epub 2012 Feb 9. Bioorg Med Chem. 2012. PMID: 22365913

8

Design, synthesis and evaluation of novel dimethylamino chalcone-O-alkylamines derivatives as potential multifunctional agents against Alzheimer's disease.

Sang Z, Song Q, Cao Z, Deng Y, Tan Z, Zhang L. Sang Z, et al. Among authors: zhang l. Eur J Med Chem. 2021 Apr 15;216:113310. doi: 10.1016/j.ejmech.2021.113310. Epub 2021 Feb 23. Eur J Med Chem. 2021. PMID: 33667847

9

Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents.

Yang GX, Huang Y, Zheng LL, Zhang L, Su L, Wu YH, Li J, Zhou LC, Huang J, Tang Y, Wang R, Ma L. Yang GX, et al. Among authors: zhang l. Eur J Med Chem. 2020 Feb 1;187:111913. doi: 10.1016/j.ejmech.2019.111913. Epub 2019 Nov 28. Eur J Med Chem. 2020. PMID: 31837501

10

Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt signaling pathways.

Fu DJ, Zhang L, Song J, Mao RW, Zhao RH, Liu YC, Hou YH, Li JH, Yang JJ, Jin CY, Li P, Zi XL, Liu HM, Zhang SY, Zhang YB. Fu DJ, et al. Among authors: zhang sy, zhang l, zhang yb. Eur J Med Chem. 2017 Feb 15;127:87-99. doi: 10.1016/j.ejmech.2016.12.027. Epub 2016 Dec 14. Eur J Med Chem. 2017. PMID: 28038329 Free PMC article.

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