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Identification of a cellularly active SIRT6 allosteric activator.
Huang Z, Zhao J, Deng W, Chen Y, Shang J, Song K, Zhang L, Wang C, Lu S, Yang X, He B, Min J, Hu H, Tan M, Xu J, Zhang Q, Zhong J, Sun X, Mao Z, Lin H, Xiao M, Chin YE, Jiang H, Xu Y, Chen G, Zhang J. Huang Z, et al. Among authors: zhang l, zhang q, zhang j. Nat Chem Biol. 2018 Dec;14(12):1118-1126. doi: 10.1038/s41589-018-0150-0. Epub 2018 Oct 29. Nat Chem Biol. 2018. PMID: 30374165
Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells.
Zhang Q, Chen Y, Ni D, Huang Z, Wei J, Feng L, Su JC, Wei Y, Ning S, Yang X, Zhao M, Qiu Y, Song K, Yu Z, Xu J, Li X, Lin H, Lu S, Zhang J. Zhang Q, et al. Among authors: zhang j. Acta Pharm Sin B. 2022 Feb;12(2):876-889. doi: 10.1016/j.apsb.2021.06.015. Epub 2021 Jul 2. Acta Pharm Sin B. 2022. PMID: 35256952 Free PMC article.
Unraveling allosteric landscapes of allosterome with ASD.
Liu X, Lu S, Song K, Shen Q, Ni D, Li Q, He X, Zhang H, Wang Q, Chen Y, Li X, Wu J, Sheng C, Chen G, Liu Y, Lu X, Zhang J. Liu X, et al. Among authors: zhang j, zhang h. Nucleic Acids Res. 2020 Jan 8;48(D1):D394-D401. doi: 10.1093/nar/gkz958. Nucleic Acids Res. 2020. PMID: 31665428 Free PMC article.
Targeting RAS phosphorylation in cancer therapy: Mechanisms and modulators.
Qiu Y, Wang Y, Chai Z, Ni D, Li X, Pu J, Chen J, Zhang J, Lu S, Lv C, Ji M. Qiu Y, et al. Among authors: zhang j. Acta Pharm Sin B. 2021 Nov;11(11):3433-3446. doi: 10.1016/j.apsb.2021.02.014. Epub 2021 Feb 25. Acta Pharm Sin B. 2021. PMID: 34900528 Free PMC article. Review.
164,628 results
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