Zhang H - Search Results

1

PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma.

Wang J, Wang C, Xu P, Li X, Lu Y, Jin D, Yin X, Jiang H, Huang J, Xiong H, Ye F, Jin J, Chen Y, Xie Y, Chen Z, Ding H, Zhang H, Liu R, Jiang H, Chen K, Yao Z, Luo C, Huang Y, Zhang Y, Zhang J. Wang J, et al. Among authors: zhang j, zhang h, zhang y. Theranostics. 2021 Mar 12;11(11):5387-5403. doi: 10.7150/thno.42345. eCollection 2021. Theranostics. 2021. PMID: 33859753 Free PMC article.

2

Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.

Wang C, Jiang H, Jin J, Xie Y, Chen Z, Zhang H, Lian F, Liu YC, Zhang C, Ding H, Chen S, Zhang N, Zhang Y, Jiang H, Chen K, Ye F, Yao Z, Luo C. Wang C, et al. Among authors: zhang n, zhang c, zhang h, zhang y. J Med Chem. 2017 Nov 9;60(21):8888-8905. doi: 10.1021/acs.jmedchem.7b01134. Epub 2017 Oct 27. J Med Chem. 2017. PMID: 29019697

3

Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays.

Sun Z, Zhang H, Chen Z, Xie Y, Jiang H, Chen L, Ding H, Zhang Y, Jiang H, Zheng M, Luo C. Sun Z, et al. Among authors: zhang h, zhang y. Bioorg Med Chem Lett. 2017 May 1;27(9):2003-2009. doi: 10.1016/j.bmcl.2017.03.012. Epub 2017 Mar 9. Bioorg Med Chem Lett. 2017. PMID: 28347667

4

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

Jiang H, Xing J, Wang C, Zhang H, Yue L, Wan X, Chen W, Ding H, Xie Y, Tao H, Chen Z, Jiang H, Chen K, Chen S, Zheng M, Zhang Y, Luo C. Jiang H, et al. Among authors: zhang h, zhang y. Org Biomol Chem. 2017 Nov 15;15(44):9352-9361. doi: 10.1039/c7ob02369c. Org Biomol Chem. 2017. PMID: 29087414

5

Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay.

Chen Z, Zhang H, Liu S, Xie Y, Jiang H, Lu W, Xu H, Yue L, Zhang Y, Ding H, Zheng M, Yu K, Chen K, Jiang H, Luo C. Chen Z, et al. Among authors: zhang h, zhang y. Medchemcomm. 2017 Mar 17;8(6):1322-1331. doi: 10.1039/c7md00083a. eCollection 2017 Jun 1. Medchemcomm. 2017. PMID: 30108844 Free PMC article.

6

Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors.

Lu W, Xiong H, Chen Y, Wang C, Zhang H, Xu P, Han J, Xiao S, Ding H, Chen Z, Lu T, Wang J, Zhang Y, Yue L, Liu YC, Zhang C, Yang Y, Jiang H, Chen K, Zhou B, Luo C. Lu W, et al. Among authors: zhang c, zhang h, zhang y. Bioorg Med Chem. 2018 Nov 1;26(20):5397-5407. doi: 10.1016/j.bmc.2018.07.048. Epub 2018 Jul 27. Bioorg Med Chem. 2018. PMID: 30297119

7

Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.

Chen W, Zhang H, Chen Z, Jiang H, Liao L, Fan S, Xing J, Xie Y, Chen S, Ding H, Chen K, Jiang H, Luo C, Zheng M, Yao Z, Huang Y, Zhang Y. Chen W, et al. Among authors: zhang h, zhang y. Oncogenesis. 2018 Nov 2;7(11):83. doi: 10.1038/s41389-018-0093-z. Oncogenesis. 2018. PMID: 30385738 Free PMC article.

8

17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells.

Zuo Y, Xu H, Chen Z, Xiong F, Zhang B, Chen K, Jiang H, Luo C, Zhang H. Zuo Y, et al. Among authors: zhang b, zhang h. Oncol Rep. 2020 Jun;43(6):1928-1944. doi: 10.3892/or.2020.7563. Epub 2020 Mar 26. Oncol Rep. 2020. PMID: 32236631 Free PMC article.

9

Machine-Learning-Assisted Approach for Discovering Novel Inhibitors Targeting Bromodomain-Containing Protein 4.

Xing J, Lu W, Liu R, Wang Y, Xie Y, Zhang H, Shi Z, Jiang H, Liu YC, Chen K, Jiang H, Luo C, Zheng M. Xing J, et al. Among authors: zhang h. J Chem Inf Model. 2017 Jul 24;57(7):1677-1690. doi: 10.1021/acs.jcim.7b00098. Epub 2017 Jul 10. J Chem Inf Model. 2017. PMID: 28636361

10

Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.

Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y. Zhou P, et al. Among authors: zhang h. Eur J Med Chem. 2018 Jan 20;144:817-842. doi: 10.1016/j.ejmech.2017.12.004. Epub 2017 Dec 7. Eur J Med Chem. 2018. PMID: 29306206

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