Zhang H - Search Results

1

Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer.

Zhang H, Schaefer A, Wang Y, Hodge RG, Blake DR, Diehl JN, Papageorge AG, Stachler MD, Liao J, Zhou J, Wu Z, Akarca FG, de Klerk LK, Derks S, Pierobon M, Hoadley KA, Wang TC, Church G, Wong KK, Petricoin EF, Cox AD, Lowy DR, Der CJ, Bass AJ. Zhang H, et al. Cancer Discov. 2020 Feb;10(2):288-305. doi: 10.1158/2159-8290.CD-19-0811. Epub 2019 Nov 26. Cancer Discov. 2020. PMID: 31771969 Free PMC article.

2

CDK4/6 or MAPK blockade enhances efficacy of EGFR inhibition in oesophageal squamous cell carcinoma.

Zhou J, Wu Z, Wong G, Pectasides E, Nagaraja A, Stachler M, Zhang H, Chen T, Zhang H, Liu JB, Xu X, Sicinska E, Sanchez-Vega F, Rustgi AK, Diehl JA, Wong KK, Bass AJ. Zhou J, et al. Among authors: zhang h. Nat Commun. 2017 Jan 6;8:13897. doi: 10.1038/ncomms13897. Nat Commun. 2017. PMID: 28059068 Free PMC article.

3

Discovery of a Pyrimidothiazolodiazepinone as a Potent and Selective Focal Adhesion Kinase (FAK) Inhibitor.

Groendyke BJ, Nabet B, Mohardt ML, Zhang H, Peng K, Koide E, Coffey CR, Che J, Scott DA, Bass AJ, Gray NS. Groendyke BJ, et al. Among authors: zhang h. ACS Med Chem Lett. 2020 Dec 14;12(1):30-38. doi: 10.1021/acsmedchemlett.0c00338. eCollection 2021 Jan 14. ACS Med Chem Lett. 2020. PMID: 33488961 Free PMC article.

4

Positive Phospho-Focal Adhesion Kinase in Gastric Cancer Associates With Poor Prognosis After Curative Resection.

Peng K, Li S, Li Q, Zhang C, Yuan Y, Liu M, Zhang L, Wang Y, Yu S, Zhang H, Liu T. Peng K, et al. Among authors: zhang l, zhang c, zhang h. Front Oncol. 2022 Aug 2;12:953938. doi: 10.3389/fonc.2022.953938. eCollection 2022. Front Oncol. 2022. PMID: 35982966 Free PMC article.

5

Development of Combination Strategies for Focal Adhesion Kinase Inhibition in Diffuse Gastric Cancer.

Peng K, Zhang F, Wang Y, Sahgal P, Li T, Zhou J, Liang X, Zhang Y, Sethi N, Liu T, Zhang H, Bass AJ. Peng K, et al. Among authors: zhang f, zhang h, zhang y. Clin Cancer Res. 2023 Jan 4;29(1):197-208. doi: 10.1158/1078-0432.CCR-22-1609. Clin Cancer Res. 2023. PMID: 36278961 Free PMC article.

6

RHOA^L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling.

Schaefer A, Hodge RG, Zhang H, Hobbs GA, Dilly J, Huynh MV, Goodwin CM, Zhang F, Diehl JN, Pierobon M, Baldelli E, Javaid S, Guthrie K, Rashid NU, Petricoin EF, Cox AD, Hahn WC, Aguirre AJ, Bass AJ, Der CJ. Schaefer A, et al. Among authors: zhang f, zhang h. Sci Signal. 2023 Dec 19;16(816):eadg5289. doi: 10.1126/scisignal.adg5289. Epub 2023 Dec 19. Sci Signal. 2023. PMID: 38113333 Free PMC article.

7

Recurrent RhoGAP gene fusion CLDN18-ARHGAP26 promotes RHOA activation and focal adhesion kinase and YAP-TEAD signalling in diffuse gastric cancer.

Zhang F, Sahu V, Peng K, Wang Y, Li T, Bala P, Aitymbayev D, Sahgal P, Schaefer A, Der CJ, Ryeom S, Yoon S, Sethi N, Bass AJ, Zhang H. Zhang F, et al. Among authors: zhang h. Gut. 2024 Apr 15:gutjnl-2023-329686. doi: 10.1136/gutjnl-2023-329686. Online ahead of print. Gut. 2024. PMID: 38621923 Free article.

8

Nuclear MYH9-induced CTNNB1 transcription, targeted by staurosporin, promotes gastric cancer cell anoikis resistance and metastasis.

Ye G, Yang Q, Lei X, Zhu X, Li F, He J, Chen H, Ling R, Zhang H, Lin T, Liang Z, Liang Y, Huang H, Guo W, Deng H, Liu H, Hu Y, Yu J, Li G. Ye G, et al. Among authors: zhang h. Theranostics. 2020 Jun 12;10(17):7545-7560. doi: 10.7150/thno.46001. eCollection 2020. Theranostics. 2020. PMID: 32685004 Free PMC article.

9

Emulation and evaluation of tumor cell combined chemotherapy in isotropic/anisotropic collagen fiber microenvironments.

Zhou L, Li G, Yao J, Wang J, Yao X, Ye Z, Zheng D, Song K, Zhang H, Zhang X, Shuai J, Ye F, Li M, Li Y, Chen G, Cheng Y, Liu H, Shaw P, Liu L. Zhou L, et al. Among authors: zhang h. Lab Chip. 2024 May 14. doi: 10.1039/d4lc00051j. Online ahead of print. Lab Chip. 2024. PMID: 38742451

10

[Aprospective study of detection and clinical significance of bone marrow tumor cells in small cell lung cancer].

Wang Y, Lu BH, Gao Y, Liu YX, Hu MM, Che NY, Lin HF, Li HX, Zhang HM, Zhang TM. Wang Y, et al. Among authors: zhang hm. Zhonghua Zhong Liu Za Zhi. 2024 May 23;46(5):419-427. doi: 10.3760/cma.j.cn112152-20231014-00193. Zhonghua Zhong Liu Za Zhi. 2024. PMID: 38742355 Chinese.

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