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The gut microbiota influences skeletal muscle mass and function in mice.
Lahiri S, Kim H, Garcia-Perez I, Reza MM, Martin KA, Kundu P, Cox LM, Selkrig J, Posma JM, Zhang H, Padmanabhan P, Moret C, Gulyás B, Blaser MJ, Auwerx J, Holmes E, Nicholson J, Wahli W, Pettersson S. Lahiri S, et al. Among authors: zhang h. Sci Transl Med. 2019 Jul 24;11(502):eaan5662. doi: 10.1126/scitranslmed.aan5662. Sci Transl Med. 2019. PMID: 31341063 Free PMC article.
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.
Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J. Pirinen E, et al. Among authors: zhang h. Cell Metab. 2014 Jun 3;19(6):1034-41. doi: 10.1016/j.cmet.2014.04.002. Epub 2014 May 8. Cell Metab. 2014. PMID: 24814482 Free PMC article.
A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function.
Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J. Ryu D, et al. Among authors: zhang h. Cell Metab. 2014 Nov 4;20(5):856-869. doi: 10.1016/j.cmet.2014.08.001. Epub 2014 Sep 4. Cell Metab. 2014. PMID: 25200183 Free article.
Protein acetylation in metabolism - metabolites and cofactors.
Menzies KJ, Zhang H, Katsyuba E, Auwerx J. Menzies KJ, et al. Among authors: zhang h. Nat Rev Endocrinol. 2016 Jan;12(1):43-60. doi: 10.1038/nrendo.2015.181. Epub 2015 Oct 27. Nat Rev Endocrinol. 2016. PMID: 26503676 Review.
KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response.
Rabhi N, Denechaud PD, Gromada X, Hannou SA, Zhang H, Rashid T, Salas E, Durand E, Sand O, Bonnefond A, Yengo L, Chavey C, Bonner C, Kerr-Conte J, Abderrahmani A, Auwerx J, Fajas L, Froguel P, Annicotte JS. Rabhi N, et al. Among authors: zhang h. Cell Rep. 2016 May 3;15(5):1051-1061. doi: 10.1016/j.celrep.2016.03.079. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117420 Free article.
NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.
Ryu D, Zhang H, Ropelle ER, Sorrentino V, Mázala DA, Mouchiroud L, Marshall PL, Campbell MD, Ali AS, Knowels GM, Bellemin S, Iyer SR, Wang X, Gariani K, Sauve AA, Cantó C, Conley KE, Walter L, Lovering RM, Chin ER, Jasmin BJ, Marcinek DJ, Menzies KJ, Auwerx J. Ryu D, et al. Among authors: zhang h. Sci Transl Med. 2016 Oct 19;8(361):361ra139. doi: 10.1126/scitranslmed.aaf5504. Sci Transl Med. 2016. PMID: 27798264 Free PMC article.
Fine-Tuning of PGC1α Expression Regulates Cardiac Function and Longevity.
Zhu X, Shen W, Yao K, Wang H, Liu B, Li T, Song L, Diao D, Mao G, Huang P, Li C, Zhang H, Zou Y, Qiu Y, Zhao Y, Wang W, Yang Y, Hu Z, Auwerx J, Loscalzo J, Zhou Y, Ju Z. Zhu X, et al. Among authors: zhang h. Circ Res. 2019 Sep 13;125(7):707-719. doi: 10.1161/CIRCRESAHA.119.315529. Epub 2019 Aug 15. Circ Res. 2019. PMID: 31412728 Free PMC article.
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