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Pilot study of large-scale production of mutant pigs by ENU mutagenesis.
Hai T, Cao C, Shang H, Guo W, Mu Y, Yang S, Zhang Y, Zheng Q, Zhang T, Wang X, Liu Y, Kong Q, Li K, Wang D, Qi M, Hong Q, Zhang R, Wang X, Jia Q, Wang X, Qin G, Li Y, Luo A, Jin W, Yao J, Huang J, Zhang H, Li M, Xie X, Zheng X, Guo K, Wang Q, Zhang S, Li L, Xie F, Zhang Y, Weng X, Yin Z, Hu K, Cong Y, Zheng P, Zou H, Xin L, Xia J, Ruan J, Li H, Zhao W, Yuan J, Liu Z, Gu W, Li M, Wang Y, Wang H, Yang S, Liu Z, Wei H, Zhao J, Zhou Q, Meng A. Hai T, et al. Among authors: zhang r, zhang s, zhang t, zhang h, zhang y. Elife. 2017 Jun 22;6:e26248. doi: 10.7554/eLife.26248. Elife. 2017. PMID: 28639938 Free PMC article.
Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity.
Zheng Q, Lin J, Huang J, Zhang H, Zhang R, Zhang X, Cao C, Hambly C, Qin G, Yao J, Song R, Jia Q, Wang X, Li Y, Zhang N, Piao Z, Ye R, Speakman JR, Wang H, Zhou Q, Wang Y, Jin W, Zhao J. Zheng Q, et al. Among authors: zhang n, zhang r, zhang h, zhang x. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9474-E9482. doi: 10.1073/pnas.1707853114. Epub 2017 Oct 23. Proc Natl Acad Sci U S A. 2017. PMID: 29078316 Free PMC article.
A pig model carrying heterozygous point mutation of NCSTN simulates familial acne inversa and reveals dysregulated cholesterol biosynthesis via the Notch-pAMPK-HMGCR pathway.
Song R, Liu K, Wang Y, Qin G, Xiao M, Liu Y, Yang J, Zong R, Yan X, Zheng Q, Zhang H, Hou N, Yao J, Wang X, Wang Y, Zhao J, Zhang X. Song R, et al. Among authors: zhang h, zhang x. Sci Bull (Beijing). 2021 Dec 15;66(23):2343-2346. doi: 10.1016/j.scib.2021.05.022. Epub 2021 May 23. Sci Bull (Beijing). 2021. PMID: 36654118 No abstract available.
119,312 results
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