Zhang G - Search Results

1

Scutellaria baicalensis enhances 5-fluorouracil-based chemotherapy via inhibition of proliferative signaling pathways.

Liu H, Liu H, Zhou Z, Chung J, Zhang G, Chang J, Parise RA, Chu E, Schmitz JC. Liu H, et al. Among authors: zhang g. Cell Commun Signal. 2023 Jun 19;21(1):147. doi: 10.1186/s12964-023-01156-7. Cell Commun Signal. 2023. PMID: 37337282 Free PMC article.

2

Overcoming acquired resistance to third-generation EGFR inhibitors by targeting activation of intrinsic apoptotic pathway through Mcl-1 inhibition, Bax activation, or both.

Ma G, Deng Y, Qian L, Vallega KA, Zhang G, Deng X, Owonikoko TK, Ramalingam SS, Fang DD, Zhai Y, Sun SY. Ma G, et al. Among authors: zhang g. Oncogene. 2022 Mar;41(12):1691-1700. doi: 10.1038/s41388-022-02200-5. Epub 2022 Jan 31. Oncogene. 2022. PMID: 35102249 Free PMC article.

3

Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.

Fan J, Lin R, Xia S, Chen D, Elf SE, Liu S, Pan Y, Xu H, Qian Z, Wang M, Shan C, Zhou L, Lei QY, Li Y, Mao H, Lee BH, Sudderth J, DeBerardinis RJ, Zhang G, Owonikoko T, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Kang S, Doetsch PW, Lonial S, Boggon TJ, Curran WJ, Chen J. Fan J, et al. Among authors: zhang g. Mol Cell. 2016 Dec 1;64(5):859-874. doi: 10.1016/j.molcel.2016.10.014. Epub 2016 Nov 17. Mol Cell. 2016. PMID: 27867011 Free PMC article.

4

Modulation of Bax and mTOR for Cancer Therapeutics.

Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus AI, Sun SY, Chen ZG, Sica GL, Ramalingam SS, Magis AT, Fu H, Khuri FR, Curran WJ, Owonikoko TK, Shin DM, Zhou J, Deng X. Li R, et al. Among authors: zhang g, zhang j. Cancer Res. 2017 Jun 1;77(11):3001-3012. doi: 10.1158/0008-5472.CAN-16-2356. Epub 2017 Apr 5. Cancer Res. 2017. PMID: 28381544 Free PMC article.

5

Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy.

Han B, Park D, Li R, Xie M, Owonikoko TK, Zhang G, Sica GL, Ding C, Zhou J, Magis AT, Chen ZG, Shin DM, Ramalingam SS, Khuri FR, Curran WJ, Deng X. Han B, et al. Among authors: zhang g. Cancer Cell. 2015 Jun 8;27(6):852-63. doi: 10.1016/j.ccell.2015.04.010. Epub 2015 May 21. Cancer Cell. 2015. PMID: 26004684 Free PMC article.

6

Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.

Yao W, Yue P, Zhang G, Owonikoko TK, Khuri FR, Sun SY. Yao W, et al. Among authors: zhang g. Cancer Lett. 2015 Aug 1;364(1):70-8. doi: 10.1016/j.canlet.2015.04.028. Epub 2015 Apr 29. Cancer Lett. 2015. PMID: 25937299 Free PMC article.

7

Inhibition of ACK1 delays and overcomes acquired resistance of EGFR mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib.

Gu J, Qian L, Zhang G, Mahajan NP, Owonikoko TK, Ramalingam SS, Sun SY. Gu J, et al. Among authors: zhang g. Lung Cancer. 2020 Dec;150:26-35. doi: 10.1016/j.lungcan.2020.09.023. Epub 2020 Sep 29. Lung Cancer. 2020. PMID: 33049499 Free PMC article.

8

Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.

Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. Shi P, et al. Among authors: zhang g. Cancer Lett. 2016 Oct 1;380(2):494-504. doi: 10.1016/j.canlet.2016.07.021. Epub 2016 Jul 19. Cancer Lett. 2016. PMID: 27450722

9

Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models.

Owonikoko TK, Zhang G, Lallani SB, Chen Z, Martinson DE, Khuri FR, Lonial S, Marcus A, Sun SY. Owonikoko TK, et al. Among authors: zhang g. PLoS One. 2019 Feb 26;14(2):e0206309. doi: 10.1371/journal.pone.0206309. eCollection 2019. PLoS One. 2019. PMID: 30807575 Free PMC article.

10

MEK or ERK inhibition effectively abrogates emergence of acquired osimertinib resistance in the treatment of epidermal growth factor receptor-mutant lung cancers.

Gu J, Yao W, Shi P, Zhang G, Owonikoko TK, Ramalingam SS, Sun SY. Gu J, et al. Among authors: zhang g. Cancer. 2020 Aug 15;126(16):3788-3799. doi: 10.1002/cncr.32996. Epub 2020 Jun 4. Cancer. 2020. PMID: 32497272 Free PMC article.

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