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Non-classical ferroptosis inhibition by a small molecule targeting PHB2.
Yang W, Mu B, You J, Tian C, Bin H, Xu Z, Zhang L, Ma R, Wu M, Zhang G, Huang C, Li L, Shao Z, Dai L, Désaubry L, Yang S. Yang W, et al. Among authors: zhang l, zhang g. Nat Commun. 2022 Dec 3;13(1):7473. doi: 10.1038/s41467-022-35294-2. Nat Commun. 2022. PMID: 36463308 Free PMC article.
Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1-(4-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal Model.
Li GB, Ma S, Yang LL, Ji S, Fang Z, Zhang G, Wang LJ, Zhong JM, Xiong Y, Wang JH, Huang SZ, Li LL, Xiang R, Niu D, Chen YC, Yang SY. Li GB, et al. Among authors: zhang g. J Med Chem. 2016 Sep 22;59(18):8293-305. doi: 10.1021/acs.jmedchem.6b00604. Epub 2016 Sep 2. J Med Chem. 2016. PMID: 27535613
Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
Yang J, Chen K, Zhang G, Yang QY, Li YS, Huang SZ, Wang YL, Yang W, Jiang XJ, Yan HX, Zhu JQ, Xiang R, Luo YF, Li WM, Wei YQ, Li LL, Yang SY. Yang J, et al. Among authors: zhang g. Eur J Med Chem. 2018 Jan 1;143:1148-1164. doi: 10.1016/j.ejmech.2017.09.018. Epub 2017 Sep 15. Eur J Med Chem. 2018. PMID: 29133048
Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model.
Li Y, Xiong Y, Zhang G, Zhang L, Yang W, Yang J, Huang L, Qiao Z, Miao Z, Lin G, Sun Q, Niu T, Chen L, Niu D, Li L, Yang S. Li Y, et al. Among authors: zhang l, zhang g. J Med Chem. 2018 Dec 27;61(24):11398-11414. doi: 10.1021/acs.jmedchem.8b01652. Epub 2018 Dec 10. J Med Chem. 2018. PMID: 30480444
37,085 results
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