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Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.
Peng S, Xiao W, Ju D, Sun B, Hou N, Liu Q, Wang Y, Zhao H, Gao C, Zhang S, Cao R, Li P, Huang H, Ma Y, Wang Y, Lai W, Ma Z, Zhang W, Huang S, Wang H, Zhang Z, Zhao L, Cai T, Zhao YL, Wang F, Nie Y, Zhi G, Yang YG, Zhang EE, Huang N. Peng S, et al. Among authors: zhang s, zhang w, zhang z, zhang ee. Sci Transl Med. 2019 Apr 17;11(488):eaau7116. doi: 10.1126/scitranslmed.aau7116. Sci Transl Med. 2019. PMID: 30996080
Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals.
Ju D, Zhang W, Yan J, Zhao H, Li W, Wang J, Liao M, Xu Z, Wang Z, Zhou G, Mei L, Hou N, Ying S, Cai T, Chen S, Xie X, Lai L, Tang C, Park N, Takahashi JS, Huang N, Qi X, Zhang EE. Ju D, et al. Among authors: zhang w, zhang ee. Sci Transl Med. 2020 May 6;12(542):eaba0769. doi: 10.1126/scitranslmed.aba0769. Sci Transl Med. 2020. PMID: 32376767
Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks.
Pei JF, Li XK, Li WQ, Gao Q, Zhang Y, Wang XM, Fu JQ, Cui SS, Qu JH, Zhao X, Hao DL, Ju D, Liu N, Carroll KS, Yang J, Zhang EE, Cao JM, Chen HZ, Liu DP. Pei JF, et al. Among authors: zhang ee, zhang y. Nat Cell Biol. 2019 Dec;21(12):1553-1564. doi: 10.1038/s41556-019-0420-4. Epub 2019 Nov 25. Nat Cell Biol. 2019. PMID: 31768048 Free PMC article.
A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the plateau pika.
Liu N, Tian H, Yu Z, Zhao H, Li W, Sang D, Lin K, Cui Y, Liao M, Xu Z, Chen C, Guo Y, Wang Y, Huang HW, Wang J, Zhang H, Wu W, Huang H, Lv S, Guo Z, Wang W, Zheng S, Wang F, Zhang Y, Cai T, Zhang EE. Liu N, et al. Among authors: zhang ee. Cell Rep. 2022 May 17;39(7):110816. doi: 10.1016/j.celrep.2022.110816. Cell Rep. 2022. PMID: 35584682 Free article.
A signalling pathway for transcriptional regulation of sleep amount in mice.
Zhou R, Wang G, Li Q, Meng F, Liu C, Gan R, Ju D, Liao M, Xu J, Sang D, Gao X, Zhou S, Wu K, Sun Q, Guo Y, Wu C, Chen Z, Chen L, Shi B, Wang H, Wang X, Li H, Cai T, Li B, Wang F, Funato H, Yanagisawa M, Zhang EE, Liu Q. Zhou R, et al. Among authors: zhang ee. Nature. 2022 Dec;612(7940):519-527. doi: 10.1038/s41586-022-05510-6. Epub 2022 Dec 7. Nature. 2022. PMID: 36477534
46 results