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BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis.
Koumaki K, Kontogianni G, Kosmidou V, Pahitsa F, Kritsi E, Zervou M, Chatziioannou A, Souliotis VL, Papadodima O, Pintzas A. Koumaki K, et al. Among authors: zervou m. Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166061. doi: 10.1016/j.bbadis.2020.166061. Epub 2020 Dec 29. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33385518 Free article.
Comparative study of the AT₁ receptor prodrug antagonist candesartan cilexetil with other sartans on the interactions with membrane bilayers.
Fotakis C, Megariotis G, Christodouleas D, Kritsi E, Zoumpoulakis P, Ntountaniotis D, Zervou M, Potamitis C, Hodzic A, Pabst G, Rappolt M, Mali G, Baldus J, Glaubitz C, Papadopoulos MG, Afantitis A, Melagraki G, Mavromoustakos T. Fotakis C, et al. Among authors: zervou m. Biochim Biophys Acta. 2012 Dec;1818(12):3107-20. doi: 10.1016/j.bbamem.2012.08.009. Epub 2012 Aug 18. Biochim Biophys Acta. 2012. PMID: 22906712 Free article.
Leveraging NMR and X-ray Data of the Free Ligands to Build Better Drugs Targeting Angiotensin II Type 1 G-Protein Coupled Receptor.
Kellici TF, Ntountaniotis D, Kritsi E, Zervou M, Zoumpoulakis P, Potamitis C, Durdagi S, Salmas RE, Ergun G, Gokdemir E, Halabalaki M, Gerothanassis IP, Liapakis G, Tzakos A, Mavromoustakos T. Kellici TF, et al. Among authors: zervou m. Curr Med Chem. 2016;23(1):36-59. doi: 10.2174/0929867323666151117122116. Curr Med Chem. 2016. PMID: 26572611 Review.
Design and Synthesis of Novel 2-Acetamido, 6-Carboxamide Substituted Benzothiazoles as Potential BRAFV600E Inhibitors - In vitro Evaluation of their Antiproliferative Activity.
Batsi Y, Antonopoulou G, Fotopoulou T, Koumaki K, Kritsi E, Potamitis C, Goulielmaki M, Skarmalioraki S, Papalouka C, Poulou-Sidiropoulou E, Kosmidou V, Douna S, Vidali MS, Gkotsi EF, Chatziioannou A, Souliotis VL, Pletsa V, Papadodima O, Zoumpourlis V, Georgiadis P, Zervou M, Pintzas A, Kostas ID. Batsi Y, et al. Among authors: zervou m. ChemMedChem. 2023 Nov 16;18(22):e202300322. doi: 10.1002/cmdc.202300322. Epub 2023 Oct 24. ChemMedChem. 2023. PMID: 37792577
146 results