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BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.
Ghouil R, Miron S, Sato K, Ristic D, van Rossum-Fikkert SE, Legrand P, Ouldali M, Winter JM, Ropars V, David G, Arteni AA, Wyman C, Knipscheer P, Kanaar R, Zelensky AN, Zinn-Justin S. Ghouil R, et al. Among authors: zelensky an. Sci Adv. 2023 Oct 27;9(43):eadi7352. doi: 10.1126/sciadv.adi7352. Epub 2023 Oct 27. Sci Adv. 2023. PMID: 37889963 Free PMC article.
Mediators of homologous DNA pairing.
Zelensky A, Kanaar R, Wyman C. Zelensky A, et al. Cold Spring Harb Perspect Biol. 2014 Oct 9;6(12):a016451. doi: 10.1101/cshperspect.a016451. Cold Spring Harb Perspect Biol. 2014. PMID: 25301930 Free PMC article. Review.
HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.
Brandsma I, Sato K, van Rossum-Fikkert SE, van Vliet N, Sleddens E, Reuter M, Odijk H, van den Tempel N, Dekkers DHW, Bezstarosti K, Demmers JAA, Maas A, Lebbink J, Wyman C, Essers J, van Gent DC, Baarends WM, Knipscheer P, Kanaar R, Zelensky AN. Brandsma I, et al. Among authors: zelensky an. Cell Rep. 2019 Jun 25;27(13):3790-3798.e7. doi: 10.1016/j.celrep.2019.05.096. Cell Rep. 2019. PMID: 31242413 Free article.
BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
Ghouil R, Miron S, Koornneef L, Veerman J, Paul MW, Le Du MH, Sleddens-Linkels E, van Rossum-Fikkert SE, van Loon Y, Felipe-Medina N, Pendas AM, Maas A, Essers J, Legrand P, Baarends WM, Kanaar R, Zinn-Justin S, Zelensky AN. Ghouil R, et al. Among authors: zelensky an. Nat Commun. 2021 Jul 29;12(1):4605. doi: 10.1038/s41467-021-24871-6. Nat Commun. 2021. PMID: 34326328 Free PMC article.
18 results