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CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects.
Glez-Vaz J, Azpilikueta A, Ochoa MC, Olivera I, Gomis G, Cirella A, Luri-Rey C, Álvarez M, Pérez-Gracia JL, Ciordia S, Eguren-Santamaria I, Alexandru R, Berraondo P, de Andrea C, Teijeira Á, Corrales F, Zapata JM, Melero I. Glez-Vaz J, et al. Among authors: zapata jm. Sci Adv. 2023 Aug 18;9(33):eadf6692. doi: 10.1126/sciadv.adf6692. Epub 2023 Aug 18. Sci Adv. 2023. PMID: 37595047 Free PMC article.
Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses.
Vladimir de la Rosa J, Tabraue C, Huang Z, Orizaola MC, Martin-Rodríguez P, Steffensen KR, Zapata JM, Boscá L, Tontonoz P, Alemany S, Treuter E, Castrillo A. Vladimir de la Rosa J, et al. Among authors: zapata jm. Adv Sci (Weinh). 2024 Mar 28:e2307201. doi: 10.1002/advs.202307201. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38549193
Editorial: Mouse Models of B Cell Malignancies.
Perez-Chacon G, Vincent-Fabert C, Zapata JM. Perez-Chacon G, et al. Among authors: zapata jm. Front Immunol. 2021 Oct 28;12:789901. doi: 10.3389/fimmu.2021.789901. eCollection 2021. Front Immunol. 2021. PMID: 34777400 Free PMC article. No abstract available.
JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia.
Aranda-Tavío H, Recio C, Martín-Acosta P, Guerra-Rodríguez M, Brito-Casillas Y, Blanco R, Junco V, León J, Montero JC, Gandullo-Sánchez L, McNaughton-Smith G, Zapata JM, Pandiella A, Amesty A, Estévez-Braun A, Fernández-Pérez L, Guerra B. Aranda-Tavío H, et al. Among authors: zapata jm. Biomed Pharmacother. 2021 Dec;144:112330. doi: 10.1016/j.biopha.2021.112330. Epub 2021 Oct 19. Biomed Pharmacother. 2021. PMID: 34673425 Free article.
Case Report: An EGFR-Targeted 4-1BB-agonistic Trimerbody Does Not Induce Hepatotoxicity in Transgenic Mice With Liver Expression of Human EGFR.
Compte M, Harwood SL, Martínez-Torrecuadrada J, Perez-Chacon G, González-García P, Tapia-Galisteo A, Van Bergen En Henegouwen PMP, Sánchez A, Fabregat I, Sanz L, Zapata JM, Alvarez-Vallina L. Compte M, et al. Among authors: zapata jm. Front Immunol. 2021 Jan 7;11:614363. doi: 10.3389/fimmu.2020.614363. eCollection 2020. Front Immunol. 2021. PMID: 33488625 Free PMC article.
From Ugi Multicomponent Reaction to Linkers for Bioconjugation.
Ramos-Tomillero I, Pérez-Chacon G, Somovilla-Crespo B, Sánchez-Madrid F, Cuevas C, Zapata JM, Domínguez JM, Rodríguez H, Albericio F. Ramos-Tomillero I, et al. Among authors: zapata jm. ACS Omega. 2020 Mar 23;5(13):7424-7431. doi: 10.1021/acsomega.0c00099. eCollection 2020 Apr 7. ACS Omega. 2020. PMID: 32280884 Free PMC article.
CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110.
Domínguez JM, Pérez-Chacón G, Guillén MJ, Muñoz-Alonso MJ, Somovilla-Crespo B, Cibrián D, Acosta-Iborra B, Adrados M, Muñoz-Calleja C, Cuevas C, Sánchez-Madrid F, Avilés P, Zapata JM. Domínguez JM, et al. Among authors: zapata jm. J Hematol Oncol. 2020 Apr 7;13(1):32. doi: 10.1186/s13045-020-00865-7. J Hematol Oncol. 2020. PMID: 32264921 Free PMC article.
95 results