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Synthesis of functionalized 2,3-diaminopropionates and their potential for directed monobactam biosynthesis.
Chem Sci. 2023 Mar 20;14(14):3923-3931. doi: 10.1039/d2sc06893a. eCollection 2023 Apr 5.
Chem Sci. 2023.
PMID: 37035696
Free PMC article.
Non-classical transpeptidases yield insight into new antibacterials.
Kumar P, Kaushik A, Lloyd EP, Li SG, Mattoo R, Ammerman NC, Bell DT, Perryman AL, Zandi TA, Ekins S, Ginell SL, Townsend CA, Freundlich JS, Lamichhane G.
Kumar P, et al. Among authors: zandi ta.
Nat Chem Biol. 2017 Jan;13(1):54-61. doi: 10.1038/nchembio.2237. Epub 2016 Nov 7.
Nat Chem Biol. 2017.
PMID: 27820797
Free PMC article.
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Competing off-loading mechanisms of meropenem from an l,d-transpeptidase reduce antibiotic effectiveness.
Zandi TA, Townsend CA.
Zandi TA, et al.
Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2008610118. doi: 10.1073/pnas.2008610118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34187885
Free PMC article.
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Structure-Activity Relationship of Penem Antibiotic Side Chains Used against Mycobacteria Reveals Highly Active Compounds.
Batchelder HR, Zandi TA, Kaushik A, Naik A, Story-Roller E, Maggioncalda EC, Lamichhane G, Nuermberger EL, Townsend CA.
Batchelder HR, et al. Among authors: zandi ta.
ACS Infect Dis. 2022 Aug 12;8(8):1627-1636. doi: 10.1021/acsinfecdis.2c00229. Epub 2022 Aug 2.
ACS Infect Dis. 2022.
PMID: 35916356
Free PMC article.
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The dabABC operon is a marker of C4-alkylated monobactam biosynthesis and responsible for (2S,3R)-diaminobutyrate production.
Li R, Lichstrahl MS, Zandi TA, Kahlert L, Townsend CA.
Li R, et al. Among authors: zandi ta.
iScience. 2024 Feb 12;27(3):109202. doi: 10.1016/j.isci.2024.109202. eCollection 2024 Mar 15.
iScience. 2024.
PMID: 38433893
Free PMC article.
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Erratum: The dabABC operon is a marker of C4-alkylated monobactam biosynthesis and responsible for (2S,3R)-diaminobutyrate production.
Li R, Lichstrahl MS, Zandi TA, Kahlert L, Townsend CA.
Li R, et al. Among authors: zandi ta.
iScience. 2024 Apr 3;27(4):109572. doi: 10.1016/j.isci.2024.109572. eCollection 2024 Apr 19.
iScience. 2024.
PMID: 38600972
Free PMC article.
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Phylogenetic and Biochemical Analyses of Mycobacterial l,d-Transpeptidases Reveal a Distinct Enzyme Class That Is Preferentially Acylated by Meropenem.
Zandi TA, Marshburn RL, Stateler PK, Brammer Basta LA.
Zandi TA, et al.
ACS Infect Dis. 2019 Dec 13;5(12):2047-2054. doi: 10.1021/acsinfecdis.9b00234. Epub 2019 Oct 14.
ACS Infect Dis. 2019.
PMID: 31597040
Free PMC article.
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