Zana A - Search Results

1

A Comparative Analysis of Fibroblast Activation Protein-Targeted Small Molecule-Drug, Antibody-Drug, and Peptide-Drug Conjugates.

Zana A, Puig-Moreno C, Bocci M, Gilardoni E, Di Nitto C, Principi L, Ravazza D, Rotta G, Prodi E, De Luca R, Neri D, Cazzamalli S. Zana A, et al. Bioconjug Chem. 2023 Jul 19;34(7):1205-1211. doi: 10.1021/acs.bioconjchem.3c00244. Epub 2023 Jul 3. Bioconjug Chem. 2023. PMID: 37399501

2

Immunotherapy with Immunocytokines and PD-1 Blockade Enhances the Anticancer Activity of Small Molecule-Drug Conjugates Targeting Carbonic Anhydrase IX.

Millul J, Krudewig C, Zana A, Dakhel Plaza S, Puca E, Villa A, Neri D, Cazzamalli S. Millul J, et al. Among authors: zana a. Mol Cancer Ther. 2021 Mar;20(3):512-522. doi: 10.1158/1535-7163.MCT-20-0361. Epub 2020 Dec 22. Mol Cancer Ther. 2021. PMID: 33443104

3

An ultra-high-affinity small organic ligand of fibroblast activation protein for tumor-targeting applications.

Millul J, Bassi G, Mock J, Elsayed A, Pellegrino C, Zana A, Dakhel Plaza S, Nadal L, Gloger A, Schmidt E, Biancofiore I, Donckele EJ, Samain F, Neri D, Cazzamalli S. Millul J, et al. Among authors: zana a. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2101852118. doi: 10.1073/pnas.2101852118. Proc Natl Acad Sci U S A. 2021. PMID: 33850024 Free PMC article.

4

Translational imaging of the fibroblast activation protein (FAP) using the new ligand [⁶⁸Ga]Ga-OncoFAP-DOTAGA.

Backhaus P, Gierse F, Burg MC, Büther F, Asmus I, Dorten P, Cufe J, Roll W, Neri D, Cazzamalli S, Millul J, Mock J, Galbiati A, Zana A, Schäfers KP, Hermann S, Weckesser M, Tio J, Wagner S, Breyholz HJ, Schäfers M. Backhaus P, et al. Among authors: zana a. Eur J Nucl Med Mol Imaging. 2022 May;49(6):1822-1832. doi: 10.1007/s00259-021-05653-0. Epub 2021 Dec 27. Eur J Nucl Med Mol Imaging. 2022. PMID: 34957527 Free PMC article.

5

A Dimeric FAP-Targeting Small-Molecule Radioconjugate with High and Prolonged Tumor Uptake.

Galbiati A, Zana A, Bocci M, Millul J, Elsayed A, Mock J, Neri D, Cazzamalli S. Galbiati A, et al. Among authors: zana a. J Nucl Med. 2022 Dec;63(12):1852-1858. doi: 10.2967/jnumed.122.264036. Epub 2022 May 19. J Nucl Med. 2022. PMID: 35589404 Free PMC article.

6

Mass Spectrometry-Based Method for the Determination of the Biodistribution of Tumor-Targeting Small Molecule-Metal Conjugates.

Gilardoni E, Zana A, Galbiati A, Sturm T, Millul J, Cazzamalli S, Neri D, Stucchi R. Gilardoni E, et al. Among authors: zana a. Anal Chem. 2022 Aug 2;94(30):10715-10721. doi: 10.1021/acs.analchem.2c01104. Epub 2022 Jul 12. Anal Chem. 2022. PMID: 35820828

7

Automated Radiosynthesis, Preliminary In Vitro/In Vivo Characterization of OncoFAP-Based Radiopharmaceuticals for Cancer Imaging and Therapy.

Bartoli F, Elsinga P, Nazario LR, Zana A, Galbiati A, Millul J, Migliorini F, Cazzamalli S, Neri D, Slart RHJA, Erba PA. Bartoli F, et al. Among authors: zana a. Pharmaceuticals (Basel). 2022 Aug 2;15(8):958. doi: 10.3390/ph15080958. Pharmaceuticals (Basel). 2022. PMID: 36015106 Free PMC article.

8

Fibroblast Activation Protein Triggers Release of Drug Payload from Non-internalizing Small Molecule Drug Conjugates in Solid Tumors.

Zana A, Galbiati A, Gilardoni E, Bocci M, Millul J, Sturm T, Stucchi R, Elsayed A, Nadal L, Cirillo M, Roll W, Stegger L, Asmus I, Backhaus P, Schäfers M, Neri D, Cazzamalli S. Zana A, et al. Clin Cancer Res. 2022 Dec 15;28(24):5440-5454. doi: 10.1158/1078-0432.CCR-22-1788. Clin Cancer Res. 2022. PMID: 36215129

9

Tumor-Targeted Interleukin 2 Boosts the Anticancer Activity of FAP-Directed Radioligand Therapeutics.

Galbiati A, Dorten P, Gilardoni E, Gierse F, Bocci M, Zana A, Mock J, Claesener M, Cufe J, Büther F, Schäfers K, Hermann S, Schäfers M, Neri D, Cazzamalli S, Backhaus P. Galbiati A, et al. Among authors: zana a. J Nucl Med. 2023 Dec 1;64(12):1934-1940. doi: 10.2967/jnumed.123.266007. J Nucl Med. 2023. PMID: 37734838

10

Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells.

Galbiati A, Bova S, Pacchiana R, Borsari C, Persico M, Zana A, Bruno S, Donadelli M, Fattorusso C, Conti P. Galbiati A, et al. Among authors: zana a. Eur J Med Chem. 2023 Jun 5;254:115286. doi: 10.1016/j.ejmech.2023.115286. Epub 2023 Apr 6. Eur J Med Chem. 2023. PMID: 37058971 Free article.

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