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Page 1
Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity.
Larson JH, Jin S, Loschi M, Bolivar Wagers S, Thangavelu G, Zaiken MC, McDonald-Hyman C, Saha A, Aguilar EG, Koehn B, Osborn MJ, Panoskaltsis-Mortari A, Macdonald KPA, Hill GR, Murphy WJ, Serody JS, Maillard I, Kean LS, Kim SV, Littman DR, Blazar BR. Larson JH, et al. Among authors: zaiken mc. Am J Transplant. 2023 Aug;23(8):1102-1115. doi: 10.1016/j.ajt.2023.01.030. Epub 2023 Mar 4. Am J Transplant. 2023. PMID: 36878433
Retinoic acid signaling acts as a rheostat to balance Treg function.
Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, Aguilar EG, Furlan SN, Brown CC, Lee YC, Hyman CM, Feser CJ, Panoskaltsis-Mortari A, Hippen KL, MacDonald KP, Murphy WJ, Maillard I, Hill GR, Munn DH, Zeiser R, Kean LS, Rathmell JC, Chi H, Noelle RJ, Blazar BR. Thangavelu G, et al. Among authors: zaiken mc. Cell Mol Immunol. 2022 Jul;19(7):820-833. doi: 10.1038/s41423-022-00869-y. Epub 2022 May 17. Cell Mol Immunol. 2022. PMID: 35581350 Free PMC article.
BET-bromodomain and EZH2 inhibitor-treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes.
Zaiken MC, Flynn R, Paz KG, Rhee SY, Jin S, Mohamed FA, Saha A, Thangavelu G, Park PMC, Hemming ML, Sage PT, Sharpe AH, DuPage M, Bluestone JA, Panoskaltsis-Mortari A, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Luznik L, Maillard I, Hill GR, MacDonald KPA, Munn DH, Serody JS, Murphy WJ, Kean LS, Zhang Y, Bradner JE, Qi J, Blazar BR. Zaiken MC, et al. Blood. 2022 May 12;139(19):2983-2997. doi: 10.1182/blood.2021014557. Blood. 2022. PMID: 35226736 Free PMC article.
Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease.
Thangavelu G, Du J, Paz KG, Loschi M, Zaiken MC, Flynn R, Taylor PA, Kirchmeier AK, Panoskaltsis-Mortari A, Luznik L, MacDonald KP, Hill GR, Maillard I, Munn DH, Serody JS, Murphy WJ, Miklos D, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Dahlberg C, Miller AT, Blazar BR. Thangavelu G, et al. Among authors: zaiken mc. Blood. 2020 Jan 2;135(1):28-40. doi: 10.1182/blood.2019000032. Blood. 2020. PMID: 31697815 Free PMC article.