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An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity.
Weisser NE, Sanches M, Escobar-Cabrera E, O'Toole J, Whalen E, Chan PWY, Wickman G, Abraham L, Choi K, Harbourne B, Samiotakis A, Rojas AH, Volkers G, Wong J, Atkinson CE, Baardsnes J, Worrall LJ, Browman D, Smith EE, Baichoo P, Cheng CW, Guedia J, Kang S, Mukhopadhyay A, Newhook L, Ohrn A, Raghunatha P, Zago-Schmitt M, Schrag JD, Smith J, Zwierzchowski P, Scurll JM, Fung V, Black S, Strynadka NCJ, Gold MR, Presta LG, Ng G, Dixit S. Weisser NE, et al. Among authors: zago schmitt m. Nat Commun. 2023 Mar 13;14(1):1394. doi: 10.1038/s41467-023-37029-3. Nat Commun. 2023. PMID: 36914633 Free PMC article.
A decreased and less sustained response to surrogates of haemostatic stress correlates with bleeding in type 1 von Willebrand disease.
Kloosterman R, Zago-Schmitt M, Grabell J, Thibeault L, Chaigneau M, Hinds M, Hopman W, Bowman M, Harpell L, Johri AM, Good D, James P. Kloosterman R, et al. Among authors: zago schmitt m. Haemophilia. 2023 Jan;29(1):370-373. doi: 10.1111/hae.14699. Epub 2022 Nov 26. Haemophilia. 2023. PMID: 36433930 No abstract available.