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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2016 | 1 |
2018 | 1 |
2019 | 1 |
2022 | 2 |
2023 | 1 |
2024 | 0 |
Search Results
6 results
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Page 1
A Single-Arm, Open-Label Phase II Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma.
Oncologist. 2023 Oct 3;28(10):919-e972. doi: 10.1093/oncolo/oyad164.
Oncologist. 2023.
PMID: 37279797
Free PMC article.
Clinical Trial.
Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis.
Greer YE, Hernandez L, Fennell EMJ, Kundu M, Voeller D, Chari R, Gilbert SF, Gilbert TSK, Ratnayake S, Tang B, Hafner M, Chen Q, Meerzaman D, Iwanowicz E, Annunziata CM, Graves LM, Lipkowitz S.
Greer YE, et al.
Cancer Res Commun. 2022 Oct 10;2(10):1144-1161. doi: 10.1158/2767-9764.CRC-22-0142.
Cancer Res Commun. 2022.
PMID: 36388465
Free PMC article.
Item in Clipboard
Characterization of TR-107, a novel chemical activator of the human mitochondrial protease ClpP.
Fennell EMJ, Aponte-Collazo LJ, Wynn JD, Drizyte-Miller K, Leung E, Greer YE, Graves PR, Iwanowicz AA, Ashamalla H, Holmuhamedov E, Lang H, Karanewsky DS, Der CJ, Houry WA, Lipkowitz S, Iwanowicz EJ, Graves LM.
Fennell EMJ, et al.
Pharmacol Res Perspect. 2022 Aug;10(4):e00993. doi: 10.1002/prp2.993.
Pharmacol Res Perspect. 2022.
PMID: 35929764
Free PMC article.
Item in Clipboard
MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer.
Greer YE, Gilbert SF, Gril B, Narwal R, Peacock Brooks DL, Tice DA, Steeg PS, Lipkowitz S.
Greer YE, et al.
Breast Cancer Res. 2019 Feb 18;21(1):27. doi: 10.1186/s13058-019-1116-1.
Breast Cancer Res. 2019.
PMID: 30777098
Free PMC article.
Item in Clipboard
ONC201 kills breast cancer cells in vitro by targeting mitochondria.
Greer YE, Porat-Shliom N, Nagashima K, Stuelten C, Crooks D, Koparde VN, Gilbert SF, Islam C, Ubaldini A, Ji Y, Gattinoni L, Soheilian F, Wang X, Hafner M, Shetty J, Tran B, Jailwala P, Cam M, Lang M, Voeller D, Reinhold WC, Rajapakse V, Pommier Y, Weigert R, Linehan WM, Lipkowitz S.
Greer YE, et al.
Oncotarget. 2018 Apr 6;9(26):18454-18479. doi: 10.18632/oncotarget.24862. eCollection 2018 Apr 6.
Oncotarget. 2018.
PMID: 29719618
Free PMC article.
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ONC201: Stressing tumors to death.
Endo Greer Y, Lipkowitz S.
Endo Greer Y, et al.
Sci Signal. 2016 Feb 16;9(415):fs1. doi: 10.1126/scisignal.aad7955.
Sci Signal. 2016.
PMID: 26884598
Free PMC article.
Review.
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