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Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone.
Levinstein MR, De Oliveira PA, Casajuana-Martin N, Quiroz C, Budinich RC, Rais R, Rea W, Ventriglia EN, Llopart N, Casadó-Anguera V, Moreno E, Walther D, Glatfelter GC, Weinshenker D, Zarate CA Jr, Casadó V, Baumann MH, Pardo L, Ferré S, Michaelides M. Levinstein MR, et al. Mol Psychiatry. 2023 Dec 25. doi: 10.1038/s41380-023-02353-z. Online ahead of print. Mol Psychiatry. 2023. PMID: 38145984
A non-canonical striatopallidal Go pathway that supports motor control.
Labouesse MA, Torres-Herraez A, Chohan MO, Villarin JM, Greenwald J, Sun X, Zahran M, Tang A, Lam S, Veenstra-VanderWeele J, Lacefield CO, Bonaventura J, Michaelides M, Chan CS, Yizhar O, Kellendonk C. Labouesse MA, et al. Nat Commun. 2023 Oct 23;14(1):6712. doi: 10.1038/s41467-023-42288-1. Nat Commun. 2023. PMID: 37872145 Free PMC article.
PET reporter systems for the brain.
Nerella SG, Michaelides M, Minamimoto T, Innis RB, Pike VW, Eldridge MAG. Nerella SG, et al. Trends Neurosci. 2023 Nov;46(11):941-952. doi: 10.1016/j.tins.2023.08.007. Epub 2023 Sep 19. Trends Neurosci. 2023. PMID: 37734962 Review.
Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging.
Bonaventura J, Boehm MA, Jedema HP, Solis O, Pignatelli M, Song X, Lu H, Richie CT, Zhang S, Gomez JL, Lam S, Morales M, Gharbawie OA, Pomper MG, Stein EA, Bradberry CW, Michaelides M. Bonaventura J, et al. Sci Transl Med. 2023 Jul 26;15(706):eadd1014. doi: 10.1126/scitranslmed.add1014. Epub 2023 Jul 26. Sci Transl Med. 2023. PMID: 37494470 Free PMC article.
Unique pharmacodynamic properties and low abuse liability of the μ-opioid receptor ligand (S)-methadone.
Michaelides M, Levinstein M, De Oliveira P, Casajuana-Martin N, Quiroz C, Budinich R, Rais R, Rea W, Ventriglia E, Llopart N, Casadó-Anguera V, Moreno E, Walther D, Glatfelter G, Weinshenker D, Zarate C, Casado V, Baumann M, Pardo L, Ferre S. Michaelides M, et al. Res Sq [Preprint]. 2023 Mar 23:rs.3.rs-2644719. doi: 10.21203/rs.3.rs-2644719/v1. Res Sq. 2023. PMID: 36993715 Free PMC article. Updated. Preprint.
Effect of Selective Lesions of Nucleus Accumbens µ-Opioid Receptor-Expressing Cells on Heroin Self-Administration in Male and Female Rats: A Study with Novel Oprm1-Cre Knock-in Rats.
Bossert JM, Mejias-Aponte CA, Saunders T, Altidor L, Emery M, Fredriksson I, Batista A, Claypool SM, Caldwell KE, Reiner DJ, Chow JJ, Foltz M, Kumar V, Seasholtz A, Hughes E, Filipiak W, Harvey BK, Richie CT, Vautier F, Gomez JL, Michaelides M, Kieffer BL, Watson SJ, Akil H, Shaham Y. Bossert JM, et al. J Neurosci. 2023 Mar 8;43(10):1692-1713. doi: 10.1523/JNEUROSCI.2049-22.2023. Epub 2023 Jan 30. J Neurosci. 2023. PMID: 36717230 Free PMC article.
20 results