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The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1.
Li H, Xiao Y, Li Q, Yao J, Yuan X, Zhang Y, Yin X, Saito Y, Fan H, Li P, Kuo WL, Halpin A, Gibbons DL, Yagita H, Zhao Z, Pang D, Ren G, Yee C, Lee JJ, Yu D. Li H, et al. Among authors: yuan x. Cancer Cell. 2022 Jan 10;40(1):36-52.e9. doi: 10.1016/j.ccell.2021.11.002. Epub 2021 Nov 24. Cancer Cell. 2022. PMID: 34822775 Free PMC article.
Inhibition of UBA6 by inosine augments tumour immunogenicity and responses.
Zhang L, Jiang L, Yu L, Li Q, Tian X, He J, Zeng L, Yang Y, Wang C, Wei Y, Jiang X, Li J, Ge X, Gu Q, Li J, Wu D, Sadler AJ, Yu D, Xu D, Gao Y, Yuan X, He B. Zhang L, et al. Among authors: yuan x. Nat Commun. 2022 Sep 15;13(1):5413. doi: 10.1038/s41467-022-33116-z. Nat Commun. 2022. PMID: 36109526 Free PMC article.
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