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GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor.
Jewell JL, Fu V, Hong AW, Yu FX, Meng D, Melick CH, Wang H, Lam WM, Yuan HX, Taylor SS, Guan KL. Jewell JL, et al. Among authors: yuan hx. Elife. 2019 May 21;8:e43038. doi: 10.7554/eLife.43038. Elife. 2019. PMID: 31112131 Free PMC article.
Regulation of mTORC1 by the Rab and Arf GTPases.
Li L, Kim E, Yuan H, Inoki K, Goraksha-Hicks P, Schiesher RL, Neufeld TP, Guan KL. Li L, et al. J Biol Chem. 2010 Jun 25;285(26):19705-9. doi: 10.1074/jbc.C110.102483. Epub 2010 May 10. J Biol Chem. 2010. PMID: 20457610 Free PMC article.
Autophagy regulation by nutrient signaling.
Russell RC, Yuan HX, Guan KL. Russell RC, et al. Among authors: yuan hx. Cell Res. 2014 Jan;24(1):42-57. doi: 10.1038/cr.2013.166. Epub 2013 Dec 17. Cell Res. 2014. PMID: 24343578 Free PMC article. Review.
Estrogen regulates Hippo signaling via GPER in breast cancer.
Zhou X, Wang S, Wang Z, Feng X, Liu P, Lv XB, Li F, Yu FX, Sun Y, Yuan H, Zhu H, Xiong Y, Lei QY, Guan KL. Zhou X, et al. J Clin Invest. 2015 May;125(5):2123-35. doi: 10.1172/JCI79573. Epub 2015 Apr 20. J Clin Invest. 2015. PMID: 25893606 Free PMC article.
The SIN1-PH Domain Connects mTORC2 to PI3K.
Yuan HX, Guan KL. Yuan HX, et al. Cancer Discov. 2015 Nov;5(11):1127-9. doi: 10.1158/2159-8290.CD-15-1125. Cancer Discov. 2015. PMID: 26526694 Free PMC article.
115 results