Yuan H - Search Results

1

Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid.

Li K, Yu XH, Maskey AR, Musa I, Wang ZZ, Garcia V, Guo A, Yang N, Srivastava K, Dunkin D, Li JX, Guo L, Cheng YC, Yuan H, Tiwari R, Li XM. Li K, et al. Among authors: yuan h. Front Pharmacol. 2023 Jan 30;13:1042756. doi: 10.3389/fphar.2022.1042756. eCollection 2022. Front Pharmacol. 2023. PMID: 36793921 Free PMC article.

2

The STING antagonist H-151 ameliorates psoriasis via suppression of STING/NF-κB-mediated inflammation.

Pan Y, You Y, Sun L, Sui Q, Liu L, Yuan H, Chen C, Liu J, Wen X, Dai L, Sun H. Pan Y, et al. Among authors: yuan h. Br J Pharmacol. 2021 Dec;178(24):4907-4922. doi: 10.1111/bph.15673. Epub 2021 Oct 30. Br J Pharmacol. 2021. PMID: 34460100 Free article.

3

Identification of novel polo-like kinase 1 inhibitors by a hybrid virtual screening.

Lu S, Sun SL, Liu HC, Chen YD, Yuan HL, Gao YP, Yang P, Lu T. Lu S, et al. Chem Biol Drug Des. 2012 Aug;80(2):328-39. doi: 10.1111/j.1747-0285.2012.01412.x. Epub 2012 Jun 8. Chem Biol Drug Des. 2012. PMID: 22583481

4

Discovery of a Novel Macrocyclic ATP Citrate Lyase Inhibitor.

Zang Y, Tai L, Hu Y, Wang Y, Sun H, Wen X, Yuan H, Dai L. Zang Y, et al. Among authors: yuan h. J Chem Inf Model. 2022 Jun 27;62(12):3123-3132. doi: 10.1021/acs.jcim.2c00345. Epub 2022 Jun 9. J Chem Inf Model. 2022. PMID: 35679529

5

Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.

Liu L, Li H, Hu K, Xu Q, Wen X, Cheng K, Chen C, Yuan H, Dai L, Sun H. Liu L, et al. Among authors: yuan h. Eur J Med Chem. 2021 Jan 1;209:112932. doi: 10.1016/j.ejmech.2020.112932. Epub 2020 Oct 14. Eur J Med Chem. 2021. PMID: 33131725

6

Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction.

Sun H, Wang J, Liu S, Zhou X, Dai L, Chen C, Xu Q, Wen X, Cheng K, Sun H, Yuan H. Sun H, et al. Among authors: yuan h. J Chem Inf Model. 2021 Oct 25;61(10):5269-5279. doi: 10.1021/acs.jcim.1c00521. Epub 2021 Sep 23. J Chem Inf Model. 2021. PMID: 34553597

7

Further Developments of the Phenyl-Pyrrolyl Pentane Series of Nonsteroidal Vitamin D Receptor Modulators as Anticancer Agents.

Hao M, Hou S, Xue L, Yuan H, Zhu L, Wang C, Wang B, Tang C, Zhang C. Hao M, et al. Among authors: yuan h. J Med Chem. 2018 Apr 12;61(7):3059-3075. doi: 10.1021/acs.jmedchem.8b00106. Epub 2018 Mar 16. J Med Chem. 2018. PMID: 29518319

8

In Silico Discovery of JMJD6 Inhibitors for Cancer Treatment.

Ran T, Xiao R, Huang Q, Yuan H, Lu T, Liu W. Ran T, et al. Among authors: yuan h. ACS Med Chem Lett. 2019 Nov 19;10(12):1609-1613. doi: 10.1021/acsmedchemlett.9b00264. eCollection 2019 Dec 12. ACS Med Chem Lett. 2019. PMID: 31857835 Free PMC article.

9

Identification of structural properties influencing the metabolism of polycyclic aromatic hydrocarbons by cytochrome P450 1A1.

Chen C, Shen J, Yang L, Zhang W, Xia R, Huan F, Gong X, Wang L, Wang C, Yuan H, Wang SL. Chen C, et al. Among authors: yuan h. Sci Total Environ. 2021 Mar 1;758:143997. doi: 10.1016/j.scitotenv.2020.143997. Epub 2020 Dec 8. Sci Total Environ. 2021. PMID: 33333309

10

Discovery and Structural Optimization of Novel Quinolone Derivatives as Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors.

Hu S, Liu Y, Ma J, Ding W, Chen H, Jiang H, Chen H, Wei S, Liu Y, Jin Q, Yuan H, Yan L. Hu S, et al. Among authors: yuan h. J Med Chem. 2023 Jul 13;66(13):8858-8875. doi: 10.1021/acs.jmedchem.3c00455. Epub 2023 Jun 19. J Med Chem. 2023. PMID: 37335602

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