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Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (-)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice.
Zhu Y, Wang L, Li J, Zhao Y, Yu X, Liu P, Deng X, Liu J, Yang F, Zhang Y, Yu J, Lai L, Wang C, Li Z, Wang L, Luo T. Zhu Y, et al. Among authors: yu x, yu j. Cell Chem Biol. 2024 Mar 21;31(3):452-464.e10. doi: 10.1016/j.chembiol.2023.10.003. Epub 2023 Oct 31. Cell Chem Biol. 2024. PMID: 37913771
Scalable Total Synthesis of (-)-Vinigrol.
Yu X, Xiao L, Wang Z, Luo T. Yu X, et al. J Am Chem Soc. 2019 Feb 27;141(8):3440-3443. doi: 10.1021/jacs.9b00621. Epub 2019 Feb 18. J Am Chem Soc. 2019. PMID: 30767520
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