Yu Q - Search Results

1

Methionine is a metabolic dependency of tumor-initiating cells.

Wang Z, Yip LY, Lee JHJ, Wu Z, Chew HY, Chong PKW, Teo CC, Ang HY, Peh KLE, Yuan J, Ma S, Choo LSK, Basri N, Jiang X, Yu Q, Hillmer AM, Lim WT, Lim TKH, Takano A, Tan EH, Tan DSW, Ho YS, Lim B, Tam WL. Wang Z, et al. Among authors: yu q. Nat Med. 2019 May;25(5):825-837. doi: 10.1038/s41591-019-0423-5. Epub 2019 May 6. Nat Med. 2019. PMID: 31061538

2

Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.

Zhao Y, Tan J, Zhuang L, Jiang X, Liu ET, Yu Q. Zhao Y, et al. Among authors: yu q. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16090-5. doi: 10.1073/pnas.0505585102. Epub 2005 Oct 21. Proc Natl Acad Sci U S A. 2005. PMID: 16243973 Free PMC article.

3

Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity.

Tan J, Zhuang L, Jiang X, Yang KK, Karuturi KM, Yu Q. Tan J, et al. Among authors: yu q. J Biol Chem. 2006 Apr 14;281(15):10508-15. doi: 10.1074/jbc.M512719200. Epub 2006 Feb 13. J Biol Chem. 2006. PMID: 16476732 Free article.

4

c-Myc overexpression sensitizes Bim-mediated Bax activation for apoptosis induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through regulating Bcl-2/Bcl-xL expression.

Jiang X, Tsang YH, Yu Q. Jiang X, et al. Among authors: yu q. Int J Biochem Cell Biol. 2007;39(5):1016-25. doi: 10.1016/j.biocel.2007.01.024. Epub 2007 Feb 2. Int J Biochem Cell Biol. 2007. PMID: 17331788

5

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.

Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET, Yu Q. Tan J, et al. Among authors: yu q. Genes Dev. 2007 May 1;21(9):1050-63. doi: 10.1101/gad.1524107. Epub 2007 Apr 16. Genes Dev. 2007. PMID: 17437993 Free PMC article.

6

DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

Jiang X, Tan J, Li J, Kivimäe S, Yang X, Zhuang L, Lee PL, Chan MT, Stanton LW, Liu ET, Cheyette BN, Yu Q. Jiang X, et al. Among authors: yu q. Cancer Cell. 2008 Jun;13(6):529-41. doi: 10.1016/j.ccr.2008.04.019. Cancer Cell. 2008. PMID: 18538736 Free PMC article.

7

miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.

Yang X, Feng M, Jiang X, Wu Z, Li Z, Aau M, Yu Q. Yang X, et al. Among authors: yu q. Genes Dev. 2009 Oct 15;23(20):2388-93. doi: 10.1101/gad.1819009. Genes Dev. 2009. PMID: 19833767 Free PMC article.

8

B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.

Tan J, Lee PL, Li Z, Jiang X, Lim YC, Hooi SC, Yu Q. Tan J, et al. Among authors: yu q. Cancer Cell. 2010 Nov 16;18(5):459-71. doi: 10.1016/j.ccr.2010.10.021. Cancer Cell. 2010. PMID: 21075311 Free article.

9

FOXQ1 regulates epithelial-mesenchymal transition in human cancers.

Qiao Y, Jiang X, Lee ST, Karuturi RK, Hooi SC, Yu Q. Qiao Y, et al. Among authors: yu q. Cancer Res. 2011 Apr 15;71(8):3076-86. doi: 10.1158/0008-5472.CAN-10-2787. Epub 2011 Feb 23. Cancer Res. 2011. PMID: 21346143

10

Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis.

Zhang WC, Shyh-Chang N, Yang H, Rai A, Umashankar S, Ma S, Soh BS, Sun LL, Tai BC, Nga ME, Bhakoo KK, Jayapal SR, Nichane M, Yu Q, Ahmed DA, Tan C, Sing WP, Tam J, Thirugananam A, Noghabi MS, Pang YH, Ang HS, Mitchell W, Robson P, Kaldis P, Soo RA, Swarup S, Lim EH, Lim B. Zhang WC, et al. Among authors: yu q. Cell. 2012 Jan 20;148(1-2):259-72. doi: 10.1016/j.cell.2011.11.050. Epub 2012 Jan 5. Cell. 2012. PMID: 22225612 Free article.

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