Yoshimura K - Search Results

1

Soluble-type small-molecule CD4 mimics as HIV entry inhibitors.

Kobayakawa T, Konno K, Ohashi N, Takahashi K, Masuda A, Yoshimura K, Harada S, Tamamura H. Kobayakawa T, et al. Among authors: yoshimura k. Bioorg Med Chem Lett. 2019 Mar 1;29(5):719-723. doi: 10.1016/j.bmcl.2019.01.011. Epub 2019 Jan 11. Bioorg Med Chem Lett. 2019. PMID: 30665681

2

Inhibition of HIV-1 replication by a peptide dimerization inhibitor of HIV-1 protease.

Davis DA, Brown CA, Singer KE, Wang V, Kaufman J, Stahl SJ, Wingfield P, Maeda K, Harada S, Yoshimura K, Kosalaraksa P, Mitsuya H, Yarchoan R. Davis DA, et al. Among authors: yoshimura k. Antiviral Res. 2006 Nov;72(2):89-99. doi: 10.1016/j.antiviral.2006.03.015. Epub 2006 Apr 21. Antiviral Res. 2006. PMID: 16687179

3

CD4 mimics targeting the mechanism of HIV entry.

Yamada Y, Ochiai C, Yoshimura K, Tanaka T, Ohashi N, Narumi T, Nomura W, Harada S, Matsushita S, Tamamura H. Yamada Y, et al. Among authors: yoshimura k. Bioorg Med Chem Lett. 2010 Jan 1;20(1):354-8. doi: 10.1016/j.bmcl.2009.10.098. Epub 2009 Nov 4. Bioorg Med Chem Lett. 2010. PMID: 19926478

4

Human immunodeficiency virus type 1 evasion of a neutralizing anti-V3 antibody involves acquisition of a potential glycosylation site in V2.

Hatada M, Yoshimura K, Harada S, Kawanami Y, Shibata J, Matsushita S. Hatada M, et al. Among authors: yoshimura k. J Gen Virol. 2010 May;91(Pt 5):1335-45. doi: 10.1099/vir.0.017426-0. Epub 2009 Dec 23. J Gen Virol. 2010. PMID: 20032207

5

Enhanced exposure of human immunodeficiency virus type 1 primary isolate neutralization epitopes through binding of CD4 mimetic compounds.

Yoshimura K, Harada S, Shibata J, Hatada M, Yamada Y, Ochiai C, Tamamura H, Matsushita S. Yoshimura K, et al. J Virol. 2010 Aug;84(15):7558-68. doi: 10.1128/JVI.00227-10. Epub 2010 May 26. J Virol. 2010. PMID: 20504942 Free PMC article.

6

CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist.

Narumi T, Ochiai C, Yoshimura K, Harada S, Tanaka T, Nomura W, Arai H, Ozaki T, Ohashi N, Matsushita S, Tamamura H. Narumi T, et al. Among authors: yoshimura k. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5853-8. doi: 10.1016/j.bmcl.2010.07.106. Epub 2010 Aug 3. Bioorg Med Chem Lett. 2010. PMID: 20728351

7

Small molecular CD4 mimics as HIV entry inhibitors.

Narumi T, Arai H, Yoshimura K, Harada S, Nomura W, Matsushita S, Tamamura H. Narumi T, et al. Among authors: yoshimura k. Bioorg Med Chem. 2011 Nov 15;19(22):6735-42. doi: 10.1016/j.bmc.2011.09.045. Epub 2011 Sep 29. Bioorg Med Chem. 2011. PMID: 22014753

8

Impact of antiretroviral pressure on selection of primary human immunodeficiency virus type 1 envelope sequences in vitro.

Harada S, Yoshimura K, Yamaguchi A, Boonchawalit S, Yusa K, Matsushita S. Harada S, et al. Among authors: yoshimura k. J Gen Virol. 2013 May;94(Pt 5):933-943. doi: 10.1099/vir.0.047167-0. Epub 2013 Jan 3. J Gen Virol. 2013. PMID: 23288425 Free PMC article.

9

CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents.

Narumi T, Arai H, Yoshimura K, Harada S, Hirota Y, Ohashi N, Hashimoto C, Nomura W, Matsushita S, Tamamura H. Narumi T, et al. Among authors: yoshimura k. Bioorg Med Chem. 2013 May 1;21(9):2518-26. doi: 10.1016/j.bmc.2013.02.041. Epub 2013 Mar 7. Bioorg Med Chem. 2013. PMID: 23535561

10

Generation of a replication-competent simian-human immunodeficiency virus, the neutralization sensitivity of which can be enhanced in the presence of a small-molecule CD4 mimic.

Otsuki H, Hishiki T, Miura T, Hashimoto C, Narumi T, Tamamura H, Yoshimura K, Matsushita S, Igarashi T. Otsuki H, et al. Among authors: yoshimura k. J Gen Virol. 2013 Dec;94(Pt 12):2710-2716. doi: 10.1099/vir.0.055590-0. Epub 2013 Sep 11. J Gen Virol. 2013. PMID: 24026672

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