Yore MM - Search Results

1

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

Liby KT, Yore MM, Sporn MB. Liby KT, et al. Among authors: yore mm. Nat Rev Cancer. 2007 May;7(5):357-69. doi: 10.1038/nrc2129. Epub 2007 Apr 19. Nat Rev Cancer. 2007. PMID: 17446857 Review.

2

The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.

Liby K, Hock T, Yore MM, Suh N, Place AE, Risingsong R, Williams CR, Royce DB, Honda T, Honda Y, Gribble GW, Hill-Kapturczak N, Agarwal A, Sporn MB. Liby K, et al. Among authors: yore mm. Cancer Res. 2005 Jun 1;65(11):4789-98. doi: 10.1158/0008-5472.CAN-04-4539. Cancer Res. 2005. PMID: 15930299

3

The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta.

Yore MM, Liby KT, Honda T, Gribble GW, Sporn MB. Yore MM, et al. Mol Cancer Ther. 2006 Dec;5(12):3232-9. doi: 10.1158/1535-7163.MCT-06-0444. Epub 2006 Dec 5. Mol Cancer Ther. 2006. PMID: 17148759

4

The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.

Liby K, Royce DB, Williams CR, Risingsong R, Yore MM, Honda T, Gribble GW, Dmitrovsky E, Sporn TA, Sporn MB. Liby K, et al. Among authors: yore mm. Cancer Res. 2007 Mar 15;67(6):2414-9. doi: 10.1158/0008-5472.CAN-06-4534. Cancer Res. 2007. PMID: 17363558

5

The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis.

Liby K, Black CC, Royce DB, Williams CR, Risingsong R, Yore MM, Liu X, Honda T, Gribble GW, Lamph WW, Sporn TA, Dmitrovsky E, Sporn MB. Liby K, et al. Among authors: yore mm. Mol Cancer Ther. 2008 May;7(5):1251-7. doi: 10.1158/1535-7163.MCT-08-0023. Mol Cancer Ther. 2008. PMID: 18483313 Free PMC article.

6

Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.

Liby K, Risingsong R, Royce DB, Williams CR, Yore MM, Honda T, Gribble GW, Lamph WW, Vannini N, Sogno I, Albini A, Sporn MB. Liby K, et al. Among authors: yore mm. Clin Cancer Res. 2008 Jul 15;14(14):4556-63. doi: 10.1158/1078-0432.CCR-08-0040. Clin Cancer Res. 2008. PMID: 18628471 Free PMC article.

7

A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.

Liby K, Yore MM, Roebuck BD, Baumgartner KJ, Honda T, Sundararajan C, Yoshizawa H, Gribble GW, Williams CR, Risingsong R, Royce DB, Dinkova-Kostova AT, Stephenson KK, Egner PA, Yates MS, Groopman JD, Kensler TW, Sporn MB. Liby K, et al. Among authors: yore mm. Cancer Res. 2008 Aug 15;68(16):6727-33. doi: 10.1158/0008-5472.CAN-08-1123. Cancer Res. 2008. PMID: 18701497 Free PMC article.

8

Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice.

Liby K, Risingsong R, Royce DB, Williams CR, Ma T, Yore MM, Sporn MB. Liby K, et al. Among authors: yore mm. Cancer Prev Res (Phila). 2009 Dec;2(12):1050-8. doi: 10.1158/1940-6207.CAPR-09-0085. Epub 2009 Dec 1. Cancer Prev Res (Phila). 2009. PMID: 19952361 Free PMC article.

9

New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress.

Sporn MB, Liby KT, Yore MM, Fu L, Lopchuk JM, Gribble GW. Sporn MB, et al. Among authors: yore mm. J Nat Prod. 2011 Mar 25;74(3):537-45. doi: 10.1021/np100826q. Epub 2011 Feb 10. J Nat Prod. 2011. PMID: 21309592 Free PMC article. Review.

10

Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.

Yates MS, Kwak MK, Egner PA, Groopman JD, Bodreddigari S, Sutter TR, Baumgartner KJ, Roebuck BD, Liby KT, Yore MM, Honda T, Gribble GW, Sporn MB, Kensler TW. Yates MS, et al. Among authors: yore mm. Cancer Res. 2006 Feb 15;66(4):2488-94. doi: 10.1158/0008-5472.CAN-05-3823. Cancer Res. 2006. PMID: 16489057

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