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Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice.
Peran I, Dakshanamurthy S, McCoy MD, Mavropoulos A, Allo B, Sebastian A, Hum NR, Sprague SC, Martin KA, Pishvaian MJ, Vietsch EE, Wellstein A, Atkins MB, Weiner LM, Quong AA, Loots GG, Yoo SS, Assefnia S, Byers SW. Peran I, et al. Among authors: yoo ss. Gastroenterology. 2021 Mar;160(4):1359-1372.e13. doi: 10.1053/j.gastro.2020.11.044. Epub 2020 Dec 9. Gastroenterology. 2021. PMID: 33307028 Free PMC article.
BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1.
Kim YS, Lee SH, Park AH, Wu C, Hong BK, Jung H, Lin SH, Yoo SS. Kim YS, et al. Among authors: yoo ss. J Immunother Cancer. 2024 Mar 14;12(3):e008303. doi: 10.1136/jitc-2023-008303. J Immunother Cancer. 2024. PMID: 38485289 Free PMC article.
Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide].
Jobson AG, Lountos GT, Lorenzi PL, Llamas J, Connelly J, Cerna D, Tropea JE, Onda A, Zoppoli G, Kondapaka S, Zhang G, Caplen NJ, Cardellina JH 2nd, Yoo SS, Monks A, Self C, Waugh DS, Shoemaker RH, Pommier Y. Jobson AG, et al. Among authors: yoo ss. J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. doi: 10.1124/jpet.109.154997. Epub 2009 Sep 9. J Pharmacol Exp Ther. 2009. PMID: 19741151 Free PMC article.
Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity.
Sun L, Li CW, Chung EM, Yang R, Kim YS, Park AH, Lai YJ, Yang Y, Wang YH, Liu J, Qiu Y, Khoo KH, Yao J, Hsu JL, Cha JH, Chan LC, Hsu JM, Lee HH, Yoo SS, Hung MC. Sun L, et al. Among authors: yoo ss. Cancer Res. 2020 Jun 1;80(11):2298-2310. doi: 10.1158/0008-5472.CAN-19-3133. Epub 2020 Mar 10. Cancer Res. 2020. PMID: 32156778 Free PMC article.
Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.
Li CW, Lim SO, Chung EM, Kim YS, Park AH, Yao J, Cha JH, Xia W, Chan LC, Kim T, Chang SS, Lee HH, Chou CK, Liu YL, Yeh HC, Perillo EP, Dunn AK, Kuo CW, Khoo KH, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Huang TH, Sahin AA, Hortobagyi GN, Yoo SS, Hung MC. Li CW, et al. Among authors: yoo ss. Cancer Cell. 2018 Feb 12;33(2):187-201.e10. doi: 10.1016/j.ccell.2018.01.009. Cancer Cell. 2018. PMID: 29438695 Free PMC article.
Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) activity by small molecule GMX1778 regulates reactive oxygen species (ROS)-mediated cytotoxicity in a p53- and nicotinic acid phosphoribosyltransferase1 (NAPRT1)-dependent manner.
Cerna D, Li H, Flaherty S, Takebe N, Coleman CN, Yoo SS. Cerna D, et al. Among authors: yoo ss. J Biol Chem. 2012 Jun 22;287(26):22408-17. doi: 10.1074/jbc.M112.357301. Epub 2012 May 8. J Biol Chem. 2012. PMID: 22570471 Free PMC article.
405 results