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[Pyrophosphate in medicine].
Goldman A, Boije af Gennis G, Xhaard H, Meri S, Yli-Kauhaluoma J. Goldman A, et al. Duodecim. 2016;132(12):1111-7. Duodecim. 2016. PMID: 27483627 Review. Finnish.
Structural Isosteres of Phosphate Groups in the Protein Data Bank.
Zhang Y, Borrel A, Ghemtio L, Regad L, Boije Af Gennäs G, Camproux AC, Yli-Kauhaluoma J, Xhaard H. Zhang Y, et al. J Chem Inf Model. 2017 Mar 27;57(3):499-516. doi: 10.1021/acs.jcim.6b00519. Epub 2017 Mar 13. J Chem Inf Model. 2017. PMID: 28234462
Azulene-based compounds for targeting orexin receptors.
Leino TO, Turku A, Yli-Kauhaluoma J, Kukkonen JP, Xhaard H, Wallén EAA. Leino TO, et al. Eur J Med Chem. 2018 Sep 5;157:88-100. doi: 10.1016/j.ejmech.2018.07.040. Epub 2018 Jul 20. Eur J Med Chem. 2018. PMID: 30077889
Discovery of Membrane-Bound Pyrophosphatase Inhibitors Derived from an Isoxazole Fragment.
Johansson NG, Turku A, Vidilaseris K, Dreano L, Khattab A, Ayuso Pérez D, Wilkinson A, Zhang Y, Tamminen M, Grazhdankin E, Kiriazis A, Fishwick CWG, Meri S, Yli-Kauhaluoma J, Goldman A, Boije Af Gennäs G, Xhaard H. Johansson NG, et al. ACS Med Chem Lett. 2020 Feb 17;11(4):605-610. doi: 10.1021/acsmedchemlett.9b00537. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292570 Free PMC article.
Exploration of Pyrazolo[1,5-a]pyrimidines as Membrane-Bound Pyrophosphatase Inhibitors.
Johansson NG, Dreano L, Vidilaseris K, Khattab A, Liu J, Lasbleiz A, Ribeiro O, Kiriazis A, Boije Af Gennäs G, Meri S, Goldman A, Yli-Kauhaluoma J, Xhaard H. Johansson NG, et al. ChemMedChem. 2021 Nov 5;16(21):3360-3367. doi: 10.1002/cmdc.202100392. Epub 2021 Oct 12. ChemMedChem. 2021. PMID: 34459148 Free PMC article.
Azulene as a biphenyl mimetic in orexin/hypocretin receptor agonists.
Leino TO, Turku A, Urvas L, Adhikari K, Oksanen J, Steynen Y, Yli-Kauhaluoma J, Xhaard H, Kukkonen JP, Wallén EAA. Leino TO, et al. Among authors: yli kauhaluoma j. Bioorg Med Chem. 2023 Jun 6;88-89:117325. doi: 10.1016/j.bmc.2023.117325. Epub 2023 May 9. Bioorg Med Chem. 2023. PMID: 37209639 Free article.
Adenosine analogs bearing phosphate isosteres as human MDO1 ligands.
Zhang Y, Jumppanen M, Maksimainen MM, Auno S, Awol Z, Ghemtio L, Venkannagari H, Lehtiö L, Yli-Kauhaluoma J, Xhaard H, Boije Af Gennäs G. Zhang Y, et al. Bioorg Med Chem. 2018 May 1;26(8):1588-1597. doi: 10.1016/j.bmc.2018.02.006. Epub 2018 Feb 13. Bioorg Med Chem. 2018. PMID: 29501416
159 results