Yeola S - Search Results

1

Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation.

Pearlstein RA, MacCannell KA, Erdemli G, Yeola S, Helmlinger G, Hu QY, Farid R, Egan W, Whitebread S, Springer C, Beck J, Wang HR, Maciejewski M, Urban L, Duca JS. Pearlstein RA, et al. Among authors: yeola s. Curr Top Med Chem. 2016;16(16):1792-818. doi: 10.2174/1568026616666160315142156. Curr Top Med Chem. 2016. PMID: 26975508 Review.

2

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.

Carson C, Raman P, Tullai J, Xu L, Henault M, Thomas E, Yeola S, Lao J, McPate M, Verkuyl JM, Marsh G, Sarber J, Amaral A, Bailey S, Lubicka D, Pham H, Miranda N, Ding J, Tang HM, Ju H, Tranter P, Ji N, Krastel P, Jain RK, Schumacher AM, Loureiro JJ, George E, Berellini G, Ross NT, Bushell SM, Erdemli G, Solomon JM. Carson C, et al. Among authors: yeola s. PLoS One. 2015 Jun 22;10(6):e0127498. doi: 10.1371/journal.pone.0127498. eCollection 2015. PLoS One. 2015. PMID: 26098886 Free PMC article.

3

The synthesis and structure-activity relationships of 3-amino-4-benzylquinolin-2-ones; discovery of novel KCNQ2 channel openers.

Hewawasam P, Chen N, Ding M, Natale JT, Boissard CG, Yeola S, Gribkoff VK, Starrett J, Dworetzky SI. Hewawasam P, et al. Among authors: yeola s. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1615-8. doi: 10.1016/j.bmcl.2004.01.073. Bioorg Med Chem Lett. 2004. PMID: 15026035

4

Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels.

Gribkoff VK, Starrett JE Jr, Dworetzky SI, Hewawasam P, Boissard CG, Cook DA, Frantz SW, Heman K, Hibbard JR, Huston K, Johnson G, Krishnan BS, Kinney GG, Lombardo LA, Meanwell NA, Molinoff PB, Myers RA, Moon SL, Ortiz A, Pajor L, Pieschl RL, Post-Munson DJ, Signor LJ, Srinivas N, Taber MT, Thalody G, Trojnacki JT, Wiener H, Yeleswaram K, Yeola SW. Gribkoff VK, et al. Among authors: yeola sw. Nat Med. 2001 Apr;7(4):471-7. doi: 10.1038/86546. Nat Med. 2001. PMID: 11283675

5

Mutations throughout the S6 region of the hKv1.5 channel alter the stability of the activation gate.

Rich TC, Yeola SW, Tamkun MM, Snyders DJ. Rich TC, et al. Am J Physiol Cell Physiol. 2002 Jan;282(1):C161-71. doi: 10.1152/ajpcell.00232.2001. Am J Physiol Cell Physiol. 2002. PMID: 11742809 Free article.

6

Determinants of antiarrhythmic drug action. Electrostatic and hydrophobic components of block of the human cardiac hKv1.5 channel.

Snyders DJ, Yeola SW. Snyders DJ, et al. Among authors: yeola sw. Circ Res. 1995 Sep;77(3):575-83. doi: 10.1161/01.res.77.3.575. Circ Res. 1995. PMID: 7641327

7

Deletion of highly conserved C-terminal sequences in the Kv1 K+ channel sub-family does not prevent expression of currents with wild-type characteristics.

Uebele VN, Yeola SW, Snyders DJ, Tamkun MM. Uebele VN, et al. Among authors: yeola sw. FEBS Lett. 1994 Feb 28;340(1-2):104-8. doi: 10.1016/0014-5793(94)80181-9. FEBS Lett. 1994. PMID: 8119390 Free article.

8

Molecular analysis of a binding site for quinidine in a human cardiac delayed rectifier K+ channel. Role of S6 in antiarrhythmic drug binding.

Yeola SW, Rich TC, Uebele VN, Tamkun MM, Snyders DJ. Yeola SW, et al. Circ Res. 1996 Jun;78(6):1105-14. doi: 10.1161/01.res.78.6.1105. Circ Res. 1996. PMID: 8635242

9

Electrophysiological and pharmacological correspondence between Kv4.2 current and rat cardiac transient outward current.

Yeola SW, Snyders DJ. Yeola SW, et al. Cardiovasc Res. 1997 Mar;33(3):540-7. doi: 10.1016/s0008-6363(96)00221-0. Cardiovasc Res. 1997. PMID: 9093524

10

Processing of procarboxypeptidase A and other zymogens in murine mast cells.

Dikov MM, Springman EB, Yeola S, Serafin WE. Dikov MM, et al. Among authors: yeola s. J Biol Chem. 1994 Oct 14;269(41):25897-904. J Biol Chem. 1994. PMID: 7929294 Free article.

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