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Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Udeochu JC, Amin S, Huang Y, Fan L, Torres ERS, Carling GK, Liu B, McGurran H, Coronas-Samano G, Kauwe G, Mousa GA, Wong MY, Ye P, Nagiri RK, Lo I, Holtzman J, Corona C, Yarahmady A, Gill MT, Raju RM, Mok SA, Gong S, Luo W, Zhao M, Tracy TE, Ratan RR, Tsai LH, Sinha SC, Gan L. Udeochu JC, et al. Among authors: yarahmady a. Nat Neurosci. 2023 May;26(5):737-750. doi: 10.1038/s41593-023-01315-6. Epub 2023 Apr 24. Nat Neurosci. 2023. PMID: 37095396 Free PMC article.
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Parra Bravo C, Giani AM, Madero-Perez J, Zhao Z, Wan Y, Samelson AJ, Wong MY, Evangelisti A, Cordes E, Fan L, Ye P, Zhu D, Pozner T, Mercedes M, Patel T, Yarahmady A, Carling GK, Sterky FH, Lee VMY, Lee EB, DeTure M, Dickson DW, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L. Parra Bravo C, et al. Among authors: yarahmady a. Cell. 2024 May 9;187(10):2446-2464.e22. doi: 10.1016/j.cell.2024.03.015. Epub 2024 Apr 5. Cell. 2024. PMID: 38582079 Free article.
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MY, Zhu D, Yu F, Xu J, Yarahmady A, Chen H, Huang Y, Amin S, Zacharioudakis E, Chen X, Holtzman DM, Mok SA, Gavathiotis E, Sinha SC, Cheng F, Luo W, Gong S, Gan L. Carling GK, et al. Among authors: yarahmady a. bioRxiv [Preprint]. 2024 Jan 25:2024.01.24.577107. doi: 10.1101/2024.01.24.577107. bioRxiv. 2024. PMID: 38328219 Free PMC article. Preprint.
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Bravo CP, Giani AM, Perez JM, Zhao Z, Samelson A, Wong MY, Evangelisti A, Fan L, Pozner T, Mercedes M, Ye P, Patel T, Yarahmady A, Carling G, Lee VMY, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L. Bravo CP, et al. Among authors: yarahmady a. bioRxiv [Preprint]. 2023 Jun 22:2023.06.19.544278. doi: 10.1101/2023.06.19.544278. bioRxiv. 2023. PMID: 37745431 Free PMC article. Updated. Preprint.