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Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs.
Hayakawa Y, Kawada M, Nishikawa H, Ochiya T, Saya H, Seimiya H, Yao R, Hayashi M, Kai C, Matsuda A, Naoe T, Ohtsu A, Okazaki T, Saji H, Sata M, Sugimura H, Sugiyama Y, Toi M, Irimura T. Hayakawa Y, et al. Among authors: yao r. Cancer Sci. 2016 Feb;107(2):189-202. doi: 10.1111/cas.12857. Cancer Sci. 2016. PMID: 26919617 Free PMC article. Review.
IFN/STAT signaling controls tumorigenesis and the drug response in colorectal cancer.
Sakahara M, Okamoto T, Oyanagi J, Takano H, Natsume Y, Yamanaka H, Kusama D, Fusejima M, Tanaka N, Mori S, Kawachi H, Ueno M, Sakai Y, Noda T, Nagayama S, Yao R. Sakahara M, et al. Among authors: yao r. Cancer Sci. 2019 Apr;110(4):1293-1305. doi: 10.1111/cas.13964. Epub 2019 Mar 22. Cancer Sci. 2019. PMID: 30724425 Free PMC article.
Integration of human inspection and artificial intelligence-based morphological typing of patient-derived organoids reveals interpatient heterogeneity of colorectal cancer.
Okamoto T, Natsume Y, Doi M, Nosato H, Iwaki T, Yamanaka H, Yamamoto M, Kawachi H, Noda T, Nagayama S, Sakanashi H, Yao R. Okamoto T, et al. Among authors: yao r. Cancer Sci. 2022 Aug;113(8):2693-2703. doi: 10.1111/cas.15396. Epub 2022 Jun 7. Cancer Sci. 2022. PMID: 35585758 Free PMC article.
Novel mouse model for Gardner syndrome generated by a large-scale N-ethyl-N-nitrosourea mutagenesis program.
Toki H, Inoue M, Motegi H, Minowa O, Kanda H, Yamamoto N, Ikeda A, Karashima Y, Matsui J, Kaneda H, Miura I, Suzuki T, Wakana S, Masuya H, Gondo Y, Shiroishi T, Akiyama T, Yao R, Noda T. Toki H, et al. Among authors: yao r. Cancer Sci. 2013 Jul;104(7):937-44. doi: 10.1111/cas.12161. Epub 2013 May 18. Cancer Sci. 2013. PMID: 23551873 Free PMC article.
1,900 results