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Hormonal therapies up-regulate MANF and overcome female susceptibility to immune checkpoint inhibitor myocarditis.
Zhang Y, Sun C, Li Y, Qin J, Amancherla K, Jing Y, Hu Q, Liang K, Zhang Z, Ye Y, Huang LA, Nguyen TK, Egranov SD, Zhao Z, Wu A, Xi Y, Yao J, Hung MC, Calin GA, Cheng J, Lim B, Lehmann LH, Salem JE, Johnson DB, Curran MA, Yu D, Han L, Darabi R, Yang L, Moslehi JJ, Lin C. Zhang Y, et al. Among authors: yao j. Sci Transl Med. 2022 Nov 2;14(669):eabo1981. doi: 10.1126/scitranslmed.abo1981. Epub 2022 Nov 2. Sci Transl Med. 2022. PMID: 36322628 Free PMC article.
Blocking immunosuppressive neutrophils deters pY696-EZH2-driven brain metastases.
Zhang L, Yao J, Wei Y, Zhou Z, Li P, Qu J, Badu-Nkansah A, Yuan X, Huang YW, Fukumura K, Mao X, Chang WC, Saunus J, Lakhani S, Huse JT, Hung MC, Yu D. Zhang L, et al. Among authors: yao j. Sci Transl Med. 2020 May 27;12(545):eaaz5387. doi: 10.1126/scitranslmed.aaz5387. Sci Transl Med. 2020. PMID: 32461334 Free PMC article.
Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1.
Yuan X, Duan Y, Xiao Y, Sun K, Qi Y, Zhang Y, Ahmed Z, Moiani D, Yao J, Li H, Zhang L, Yuzhalin AE, Li P, Zhang C, Badu-Nkansah A, Saito Y, Liu X, Kuo WL, Ying H, Sun SC, Chang JC, Tainer JA, Yu D. Yuan X, et al. Among authors: yao j. Cancer Discov. 2022 Jul 6;12(7):1742-1759. doi: 10.1158/2159-8290.CD-21-0900. Cancer Discov. 2022. PMID: 35420681 Free PMC article.
Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion.
Sun C, Ye Y, Tan Z, Liu Y, Li Y, Hu W, Liang K, Egranov SD, Huang LA, Zhang Z, Zhang Y, Yao J, Nguyen TK, Zhao Z, Wu A, Marks JR, Caudle AS, Sahin AA, Gao J, Gammon ST, Piwnica-Worms D, Hu J, Chiao PJ, Yu D, Hung MC, Curran MA, Calin GA, Ying H, Han L, Lin C, Yang L. Sun C, et al. Among authors: yao j. Sci Adv. 2023 Feb 3;9(5):eadd6995. doi: 10.1126/sciadv.add6995. Epub 2023 Feb 1. Sci Adv. 2023. PMID: 36724291 Free PMC article.
Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation.
Zhang Y, Zhao Z, Huang LA, Liu Y, Yao J, Sun C, Li Y, Zhang Z, Ye Y, Yuan F, Nguyen TK, Garlapati NR, Wu A, Egranov SD, Caudle AS, Sahin AA, Lim B, Beretta L, Calin GA, Yu D, Hung MC, Curran MA, Rezvani K, Gan B, Tan Z, Han L, Lin C, Yang L. Zhang Y, et al. Among authors: yao j. Cell Metab. 2023 Aug 8;35(8):1457-1473.e13. doi: 10.1016/j.cmet.2023.05.009. Epub 2023 Jun 16. Cell Metab. 2023. PMID: 37329887 Free article.
BRCA1-mediated dual regulation of ferroptosis exposes a vulnerability to GPX4 and PARP co-inhibition in BRCA1-deficient cancers.
Lei G, Mao C, Horbath AD, Yan Y, Cai S, Yao J, Jiang Y, Sun M, Liu X, Cheng J, Xu Z, Lee H, Li Q, Lu Z, Zhuang L, Chen MK, Alapati A, Yap TA, Hung MC, You MJ, Piwnica-Worms H, Gan B. Lei G, et al. Among authors: yao j. Cancer Discov. 2024 Mar 28. doi: 10.1158/2159-8290.CD-23-1220. Online ahead of print. Cancer Discov. 2024. PMID: 38552003
Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer.
Fu J, Ling J, Li CF, Tsai CL, Yin W, Hou J, Chen P, Cao Y, Kang Y, Sun Y, Xia X, Jiang Z, Furukawa K, Lu Y, Wu M, Huang Q, Yao J, Hawke DH, Pan BF, Zhao J, Huang J, Wang H, Bahassi EIM, Stambrook PJ, Huang P, Fleming JB, Maitra A, Tainer JA, Hung MC, Lin C, Chiao PJ. Fu J, et al. Among authors: yao j. Nat Commun. 2024 Apr 11;15(1):3149. doi: 10.1038/s41467-024-47242-3. Nat Commun. 2024. PMID: 38605037 Free PMC article.
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