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The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes.
Huang Q, Wu X, Wang Z, Chen X, Wang L, Lu Y, Xiong D, Liu Q, Tian Y, Lin H, Guo J, Wen S, Dong W, Yang X, Yuan Y, Yue Z, Lei S, Wu Q, Ran L, Xie L, Wang Y, Gao L, Tian Q, Zhou X, Sun B, Xu L, Tang Z, Ye L. Huang Q, et al. Among authors: yang x. Cell. 2022 Oct 27;185(22):4049-4066.e25. doi: 10.1016/j.cell.2022.09.020. Epub 2022 Oct 7. Cell. 2022. PMID: 36208623 Free article.
Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19.
Chen X, Pan Z, Yue S, Yu F, Zhang J, Yang Y, Li R, Liu B, Yang X, Gao L, Li Z, Lin Y, Huang Q, Xu L, Tang J, Hu L, Zhao J, Liu P, Zhang G, Chen Y, Deng K, Ye L. Chen X, et al. Among authors: yang x, yang y. Signal Transduct Target Ther. 2020 Sep 2;5(1):180. doi: 10.1038/s41392-020-00301-9. Signal Transduct Target Ther. 2020. PMID: 32879307 Free PMC article.
A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD.
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L. Wang X, et al. Among authors: yang x, yang y. Signal Transduct Target Ther. 2022 Apr 5;7(1):114. doi: 10.1038/s41392-022-00954-8. Signal Transduct Target Ther. 2022. PMID: 35383141 Free PMC article.
Nasal Spray of Neutralizing Monoclonal Antibody 35B5 Confers Potential Prophylaxis Against Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern: A Small-Scale Clinical Trial.
Lin Y, Yue S, Yang Y, Yang S, Pan Z, Yang X, Gao L, Zhou J, Li Z, Hu L, Tang J, Wu Q, Lei S, Tian Q, Wang Y, Hao Y, Xu L, Huang Q, Zhu B, Chen Y, Chen X, Ye L. Lin Y, et al. Among authors: yang s, yang x, yang y. Clin Infect Dis. 2023 Feb 8;76(3):e336-e341. doi: 10.1093/cid/ciac448. Clin Infect Dis. 2023. PMID: 35666466 Free PMC article. Clinical Trial.
PD-1/PD-L1 blockade restores tumor-induced COVID-19 vaccine bluntness.
Chen X, Lin Y, Yue S, Yang Y, Yang X, He J, Gao L, Li Z, Hu L, Tang J, Wang Y, Tian Q, Hao Y, Xu L, Huang Q, Cao Y, Ye L. Chen X, et al. Among authors: yang x, yang y. Vaccine. 2023 Jul 31;41(34):4986-4995. doi: 10.1016/j.vaccine.2023.06.053. Epub 2023 Jun 20. Vaccine. 2023. PMID: 37400286 Free PMC article.
Dopamine Receptor 1 Impedes ILC2-Mediated Antitumor Immunity.
Wang X, Chen X, Chen J, Liao C, Yang X, Zhou J, Liu S, Ye S, Zheng Y, Huang L, Zhao J, Ye L, Huang B, Cao Y. Wang X, et al. Among authors: yang x. J Immunol. 2023 Nov 1;211(9):1418-1425. doi: 10.4049/jimmunol.2300220. J Immunol. 2023. PMID: 37728417
An oncolytic virus delivering tumor-irrelevant bystander T cell epitopes induces anti-tumor immunity and potentiates cancer immunotherapy.
Chen X, Zhao J, Yue S, Li Z, Duan X, Lin Y, Yang Y, He J, Gao L, Pan Z, Yang X, Su X, Huang M, Li X, Zhao Y, Zhang X, Li Z, Hu L, Tang J, Hao Y, Tian Q, Wang Y, Xu L, Huang Q, Cao Y, Chen Y, Zhu B, Li Y, Bai F, Zhang G, Ye L. Chen X, et al. Among authors: yang x, yang y. Nat Cancer. 2024 Apr 12. doi: 10.1038/s43018-024-00760-x. Online ahead of print. Nat Cancer. 2024. PMID: 38609488
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