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Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
Meng D, Yang Q, Wang H, Melick CH, Navlani R, Frank AR, Jewell JL. Meng D, et al. Among authors: yang q. J Biol Chem. 2020 Mar 6;295(10):2890-2899. doi: 10.1074/jbc.AC119.011578. Epub 2020 Feb 4. J Biol Chem. 2020. PMID: 32019866 Free PMC article.
ArfGAP1 inhibits mTORC1 lysosomal localization and activation.
Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL. Meng D, et al. Among authors: yang q. EMBO J. 2021 Jun 15;40(12):e106412. doi: 10.15252/embj.2020106412. Epub 2021 May 14. EMBO J. 2021. PMID: 33988249 Free PMC article.
SNAT7 regulates mTORC1 via macropinocytosis.
Meng D, Yang Q, Jeong MH, Curukovic A, Tiwary S, Melick CH, Lama-Sherpa TD, Wang H, Huerta-Rosario M, Urquhart G, Zacharias LG, Lewis C, DeBerardinis RJ, Jewell JL. Meng D, et al. Among authors: yang q. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2123261119. doi: 10.1073/pnas.2123261119. Epub 2022 May 13. Proc Natl Acad Sci U S A. 2022. PMID: 35561222 Free PMC article.
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