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LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.
Sheng W, LaFleur MW, Nguyen TH, Chen S, Chakravarthy A, Conway JR, Li Y, Chen H, Yang H, Hsu PH, Van Allen EM, Freeman GJ, De Carvalho DD, He HH, Sharpe AH, Shi Y. Sheng W, et al. Among authors: yang h. Cell. 2018 Jul 26;174(3):549-563.e19. doi: 10.1016/j.cell.2018.05.052. Epub 2018 Jun 21. Cell. 2018. PMID: 29937226 Free PMC article.
Pseudogene-mediated DNA demethylation leads to oncogene activation.
Kwon J, Liu YV, Gao C, Bassal MA, Jones AI, Yang J, Chen Z, Li Y, Yang H, Chen L, Di Ruscio A, Tay Y, Chai L, Tenen DG. Kwon J, et al. Among authors: yang h, yang j. Sci Adv. 2021 Oct;7(40):eabg1695. doi: 10.1126/sciadv.abg1695. Epub 2021 Oct 1. Sci Adv. 2021. PMID: 34597139 Free PMC article.
Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.
Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber PB, Di Ruscio A, Welner RS, Ebralidze A, Zhang J, Levantini E, Lefebvre V, Valk PJ, Delwel R, Hoogenkamp M, Nerlov C, Cammenga J, Saez B, Scadden DT, Bonifer C, Ye M, Tenen DG. Zhang H, et al. Among authors: yang h. Cancer Cell. 2013 Nov 11;24(5):575-88. doi: 10.1016/j.ccr.2013.09.018. Epub 2013 Oct 31. Cancer Cell. 2013. PMID: 24183681 Free PMC article.
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