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YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways.
Chen Q, Yang C, Chen L, Zhang JJ, Ge WL, Yuan H, Meng LD, Huang XM, Shen P, Miao Y, Jiang KR. Chen Q, et al. Among authors: yang c. Br J Cancer. 2019 Nov;121(11):912-921. doi: 10.1038/s41416-019-0604-5. Epub 2019 Oct 21. Br J Cancer. 2019. PMID: 31631174 Free PMC article.
BACKGROUND: Pancreatic cancer (PDAC) is a highly invasive cancer with poor prognosis. Recent research has found that the transcription factor Yin Yang 1 (YY1) plays an inhibitory role in the development of pancreatic cancer. ...The expression of TPPP in pancreatic cancer w …
BACKGROUND: Pancreatic cancer (PDAC) is a highly invasive cancer with poor prognosis. Recent research has found that the transcription facto …
Yin Yang-1 increases apoptosis through Bax activation in pancreatic cancer cells.
Zhang JJ, Zhu Y, Yang C, Liu X, Peng YP, Jiang KR, Miao Y, Xu ZK. Zhang JJ, et al. Among authors: yang c. Oncotarget. 2016 May 10;7(19):28498-509. doi: 10.18632/oncotarget.8654. Oncotarget. 2016. PMID: 27074573 Free PMC article.
The transcriptional regulator Yin Yang-1 (YY1) is a tumor suppressor known to be overexpressed in pancreatic cancer. ...Moreover, YY1 promoted pancreatic cancer cell apoptosis through Bax transcriptional activation and subsequent translocation of Bax to the mitochondrial m …
The transcriptional regulator Yin Yang-1 (YY1) is a tumor suppressor known to be overexpressed in pancreatic cancer. ...Moreover, YY1 …
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