Polycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway.
Yu W, Kong T, Beaudry S, Tran M, Negoro H, Yanamadala V, Denker BM.
Yu W, et al. Among authors: yanamadala v.
J Biol Chem. 2010 Apr 2;285(14):10243-51. doi: 10.1074/jbc.M109.070821. Epub 2010 Jan 27.
J Biol Chem. 2010.
PMID: 20106977
Free PMC article.
Recently, we reported increased apoptosis in Madin-Darby canine kidney (MDCK) cells through Galpha(12) stimulation of JNK and degradation of the anti-apoptotic protein Bcl-2 (Yanamadala, V., Negoro, H., Gunaratnam, L., Kong, T., and Denker, B. ...
Recently, we reported increased apoptosis in Madin-Darby canine kidney (MDCK) cells through Galpha(12) stimulation of JNK and degradation of …