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A novel glycerophosphodiester phosphodiesterase, GDE5, controls skeletal muscle development via a non-enzymatic mechanism.
Okazaki Y, Ohshima N, Yoshizawa I, Kamei Y, Mariggiò S, Okamoto K, Maeda M, Nogusa Y, Fujioka Y, Izumi T, Ogawa Y, Shiro Y, Wada M, Kato N, Corda D, Yanaka N. Okazaki Y, et al. Among authors: yanaka n. J Biol Chem. 2010 Sep 3;285(36):27652-63. doi: 10.1074/jbc.M110.106708. Epub 2010 Jun 24. J Biol Chem. 2010. PMID: 20576599 Free PMC article.
GDE5 inhibition accumulates intracellular glycerophosphocholine and suppresses adipogenesis at a mitotic clonal expansion stage.
Okazaki Y, Nakamura K, Takeda S, Yoshizawa I, Yoshida F, Ohshima N, Izumi T, Klein JD, Kumrungsee T, Sands JM, Yanaka N. Okazaki Y, et al. Among authors: yanaka n. Am J Physiol Cell Physiol. 2019 Feb 1;316(2):C162-C174. doi: 10.1152/ajpcell.00305.2018. Epub 2018 Nov 21. Am J Physiol Cell Physiol. 2019. PMID: 30462540 Free PMC article.
Mammalian glycerophosphodiester phosphodiesterases.
Yanaka N. Yanaka N. Biosci Biotechnol Biochem. 2007 Aug;71(8):1811-8. doi: 10.1271/bbb.70062. Epub 2007 Aug 7. Biosci Biotechnol Biochem. 2007. PMID: 17690467 Free article. Review.
99 results