Yanai R - Search Results

1

The alternative complement pathway regulates pathological angiogenesis in the retina.

Sweigard JH, Yanai R, Gaissert P, Saint-Geniez M, Kataoka K, Thanos A, Stahl GL, Lambris JD, Connor KM. Sweigard JH, et al. Among authors: yanai r. FASEB J. 2014 Jul;28(7):3171-82. doi: 10.1096/fj.14-251041. Epub 2014 Mar 25. FASEB J. 2014. PMID: 24668752 Free PMC article.

Together, our data implicate the alternative complement pathway in facilitating neovessel clearance by down-regulating the complement inhibitor Cd55 specifically on neovessels, allowing for their targeted removal while leaving the established vasculature intact.-Sweigard, J. H., …

Together, our data implicate the alternative complement pathway in facilitating neovessel clearance by down-regulating the complement inhibi …

2

Inhibition of the alternative complement pathway preserves photoreceptors after retinal injury.

Sweigard JH, Matsumoto H, Smith KE, Kim LA, Paschalis EI, Okonuki Y, Castillejos A, Kataoka K, Hasegawa E, Yanai R, Husain D, Lambris JD, Vavvas D, Miller JW, Connor KM. Sweigard JH, et al. Among authors: yanai r. Sci Transl Med. 2015 Jul 22;7(297):297ra116. doi: 10.1126/scitranslmed.aab1482. Sci Transl Med. 2015. PMID: 26203084 Free PMC article.

3

Complement involvement in neovascular ocular diseases.

Yanai R, Thanos A, Connor KM. Yanai R, et al. Adv Exp Med Biol. 2012;946:161-83. doi: 10.1007/978-1-4614-0106-3_10. Adv Exp Med Biol. 2012. PMID: 21948368 Review.

4

Cytochrome P450-generated metabolites derived from ω-3 fatty acids attenuate neovascularization.

Yanai R, Mulki L, Hasegawa E, Takeuchi K, Sweigard H, Suzuki J, Gaissert P, Vavvas DG, Sonoda KH, Rothe M, Schunck WH, Miller JW, Connor KM. Yanai R, et al. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9603-8. doi: 10.1073/pnas.1401191111. Epub 2014 Jun 16. Proc Natl Acad Sci U S A. 2014. PMID: 24979774 Free PMC article.

5

EGF-like-domain-7 is required for VEGF-induced Akt/ERK activation and vascular tube formation in an ex vivo angiogenesis assay.

Takeuchi K, Yanai R, Kumase F, Morizane Y, Suzuki J, Kayama M, Brodowska K, Nakazawa M, Miller JW, Connor KM, Vavvas DG. Takeuchi K, et al. Among authors: yanai r. PLoS One. 2014 Mar 19;9(3):e91849. doi: 10.1371/journal.pone.0091849. eCollection 2014. PLoS One. 2014. PMID: 24647208 Free PMC article.

6

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.

Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM. Hasegawa E, et al. Among authors: yanai r. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7545-E7553. doi: 10.1073/pnas.1620898114. Epub 2017 Aug 21. Proc Natl Acad Sci U S A. 2017. PMID: 28827330 Free PMC article.

7

Attenuation of choroidal neovascularization by dietary intake of ω-3 long-chain polyunsaturated fatty acids and lutein in mice.

Yanai R, Chen S, Uchi SH, Nanri T, Connor KM, Kimura K. Yanai R, et al. PLoS One. 2018 Apr 25;13(4):e0196037. doi: 10.1371/journal.pone.0196037. eCollection 2018. PLoS One. 2018. PMID: 29694386 Free PMC article.

8

Dietary Omega-3 Fatty Acids Suppress Experimental Autoimmune Uveitis in Association with Inhibition of Th1 and Th17 Cell Function.

Shoda H, Yanai R, Yoshimura T, Nagai T, Kimura K, Sobrin L, Connor KM, Sakoda Y, Tamada K, Ikeda T, Sonoda KH. Shoda H, et al. Among authors: yanai r. PLoS One. 2015 Sep 22;10(9):e0138241. doi: 10.1371/journal.pone.0138241. eCollection 2015. PLoS One. 2015. PMID: 26393358 Free PMC article.

9

Dendritic cells mediate the anti-inflammatory action of omega-3 long-chain polyunsaturated fatty acids in experimental autoimmune uveitis.

Uchi SH, Yanai R, Kobayashi M, Hatano M, Kobayashi Y, Yamashiro C, Nagai T, Tokuda K, Connor KM, Sonoda KH, Kimura K. Uchi SH, et al. Among authors: yanai r. PLoS One. 2019 Jul 23;14(7):e0219405. doi: 10.1371/journal.pone.0219405. eCollection 2019. PLoS One. 2019. PMID: 31335861 Free PMC article.

10

Correction: Dendritic cells mediate the anti-inflammatory action of omega-3 long-chain polyunsaturated fatty acids in experimental autoimmune uveitis.

Uchi SH, Yanai R, Kobayashi M, Hatano M, Kobayashi Y, Yamashiro C, Nagai T, Tokuda K, Connor KM, Sonoda KH, Kimura K. Uchi SH, et al. Among authors: yanai r. PLoS One. 2020 Mar 27;15(3):e0231277. doi: 10.1371/journal.pone.0231277. eCollection 2020. PLoS One. 2020. PMID: 32218588 Free PMC article.

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