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IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma.
Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetrean O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, Ikeda S, Shimada H, Minami N, Malhotra A, Morioka S, Ban Y, Asano M, Flanary VL, Ramkissoon A, Chow LML, Kiyokawa J, Mashimo T, Lucey G, Mareninov S, Ozawa T, Onishi N, Okumura K, Terakawa J, Daikoku T, Wise-Draper T, Majd N, Kofuji K, Sasaki M, Mori M, Kanemura Y, Smith EP, Anastasiou D, Wakimoto H, Holland EC, Yong WH, Horbinski C, Nakano I, DeBerardinis RJ, Bachoo RM, Mischel PS, Yasui W, Suematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT. Kofuji S, et al. Among authors: yamashita d. Nat Cell Biol. 2019 Aug;21(8):1003-1014. doi: 10.1038/s41556-019-0363-9. Epub 2019 Aug 1. Nat Cell Biol. 2019. PMID: 31371825 Free PMC article.
Targeting glioma-initiating cells via the tyrosine metabolic pathway.
Yamashita D, Bernstock JD, Elsayed G, Sadahiro H, Mohyeldin A, Chagoya G, Ilyas A, Mooney J, Estevez-Ordonez D, Yamaguchi S, Flanary VL, Hackney JR, Bhat KP, Kornblum HI, Zamboni N, Kim SH, Chiocca EA, Nakano I. Yamashita D, et al. J Neurosurg. 2020 Feb 14;134(3):721-732. doi: 10.3171/2019.11.JNS192028. J Neurosurg. 2020. PMID: 32059178 Free PMC article.
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy.
Bastola S, Pavlyukov MS, Yamashita D, Ghosh S, Cho H, Kagaya N, Zhang Z, Minata M, Lee Y, Sadahiro H, Yamaguchi S, Komarova S, Yang E, Markert J, Nabors LB, Bhat K, Lee J, Chen Q, Crossman DK, Shin-Ya K, Nam DH, Nakano I. Bastola S, et al. Among authors: yamashita d. Nat Commun. 2020 Sep 16;11(1):4660. doi: 10.1038/s41467-020-18189-y. Nat Commun. 2020. PMID: 32938908 Free PMC article.
Prediction of Glioma Stemlike Cell Infiltration in the Non-Contrast-Enhancing Area by Quantitative Measurement of Lactate on Magnetic Resonance Spectroscopy in Glioblastoma.
Inoue A, Nishikawa M, Ohnishi T, Yano H, Kanemura Y, Ohtsuka Y, Ozaki S, Nakamura Y, Matsumoto S, Suehiro S, Yamashita D, Shigekawa S, Watanabe H, Kitazawa R, Tanaka J, Kunieda T. Inoue A, et al. Among authors: yamashita d. World Neurosurg. 2021 Sep;153:e76-e95. doi: 10.1016/j.wneu.2021.06.044. Epub 2021 Jun 16. World Neurosurg. 2021. PMID: 34144167
GANP protein encoded on human chromosome 21/mouse chromosome 10 is associated with resistance to mammary tumor development.
Kuwahara K, Yamamoto-Ibusuki M, Zhang Z, Phimsen S, Gondo N, Yamashita H, Takeo T, Nakagata N, Yamashita D, Fukushima Y, Yamamoto Y, Iwata H, Saya H, Kondo E, Matsuo K, Takeya M, Iwase H, Sakaguchi N. Kuwahara K, et al. Among authors: yamashita h, yamashita d. Cancer Sci. 2016 Apr;107(4):469-77. doi: 10.1111/cas.12883. Epub 2016 Feb 9. Cancer Sci. 2016. PMID: 26749495 Free PMC article.
Tumor edge-to-core transition promotes malignancy in primary-to-recurrent glioblastoma progression in a PLAGL1/CD109-mediated mechanism.
Li C, Cho HJ, Yamashita D, Abdelrashid M, Chen Q, Bastola S, Chagoya G, Elsayed GA, Komarova S, Ozaki S, Ohtsuka Y, Kunieda T, Kornblum HI, Kondo T, Nam DH, Nakano I. Li C, et al. Among authors: yamashita d. Neurooncol Adv. 2020 Nov 27;2(1):vdaa163. doi: 10.1093/noajnl/vdaa163. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33392508 Free PMC article.
Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis.
Ozaki S, Umakoshi A, Yano H, Ohsumi S, Sumida Y, Hayase E, Usa E, Islam A, Choudhury ME, Nishi Y, Yamashita D, Ohtsuka Y, Nishikawa M, Inoue A, Suehiro S, Kuwabara J, Watanabe H, Takada Y, Watanabe Y, Nakano I, Kunieda T, Tanaka J. Ozaki S, et al. Among authors: yamashita d. Neoplasia. 2021 Aug;23(8):754-765. doi: 10.1016/j.neo.2021.06.001. Epub 2021 Jul 3. Neoplasia. 2021. PMID: 34229297 Free PMC article.
382 results